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Horm Metab Res 1972; 4(3): 187-190
DOI: 10.1055/s-0028-1094046
Originals

© Georg Thieme Verlag KG Stuttgart · New York

Augmentation by Dihydroergotamine of Lipolysis Stimulated by Whole and Pepsin-Digested Human Growth Hormone[*]

A.  Kowadlo-Silbergeld , I.  Klipper , S.  Assa , Z.  Laron
  • Pediatric Metabolic and Endocrine Service and Rogoff-Wellcome Medical Research Institute, Beilinson Hospital, Department of Physiology, Tel Aviv University Medical School, Israel
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Publication History

Publication Date:
07 January 2009 (online)

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Abstract

Dihydroergotamine was found to significantly enhance the lipolytic response of rat adipocytes and tissue sements to human growth hormone, whether whole or pepsin-digested. The effect was dexamethasone dependent, and was inhibited by cycloheximide.

Key words

Lipolysis - Isolated Fat Cells - Dihydroergotamine - Human Growth Hormone - Peptic Digestion - Cycloheximide

1 Presented in part at the 2nd International Symposium on Growth Hormone, Milan, May 5-7,1971.

1 Presented in part at the 2nd International Symposium on Growth Hormone, Milan, May 5-7,1971.

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