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Planta Med 1979; 36(7): 193-195
DOI: 10.1055/s-0028-1097268
DOI: 10.1055/s-0028-1097268
Research Articles
© Georg Thieme Verlag Stuttgart · New York
Inhibition of 3',5'–AMP Phosphodiesterase by Biflavonoids and Xanthones
Further Information
Publication History
Publication Date:
13 January 2009 (online)
Abstract
Biflavonoids and xanthones were assayed for their ability to inhibit the breakdown of cyclic AMP by a commercial beef–heart phosphodiesterase. Most of the biflavonoids were active in the micromolar range, while amento–flavone was ten times as potent; two xanthones had I50 values of about 30 μM.
Key Word Index
Flavonoids - Biflavonoids - Xanthones - CAMP Phosphodiesterase Inhibitors