Planta Med 1973; 24(8): 371-374
DOI: 10.1055/s-0028-1099511
© Georg Thieme Verlag Stuttgart · New York

NEW ALKALOIDS FROM ERYTHROPHLEUM SPECIES

A. Cronlund1
  • Department of Pharmacognosy, Faculty of Pharmacy Stockholm, Sweden
1 Paper presented at the „20. Tagung der Gesellschaft für Arzneipflanzenforschung” Helsinki, Finland, July 20.–29.1972.
Further Information

Publication History

Publication Date:
14 January 2009 (online)

Abstract

The lecture reports on two new alkaloids from Erythrophleum ivorense, namely: 3(3–methylcrotonyl)cassaine (VI) and a 19–hydroxy substituted alkaloid with a tentative structure (VII). The isolation of cassamide, erythrophlamide, cassaide [12] and 3β–acetoxy–7β–hydroxy–N–(β–hydroxyethyl)–N–methyl–E–13(15)–cassen–16–amide (XII) from E. guineense is also reported. The isomerism of the amide linkage in the latter compounds as well as some notes on the structure–activity relationship of erythrophleum alkaloids are discussed. Finally an investigation of E. africanum and some aspects of undiscovered erythrophleum alkaloids are mentioned.

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