Download PDF
Planta Med 2009; 75(5): 534-537
DOI: 10.1055/s-0029-1185356
Natural Product Chemistry
Letter
© Georg Thieme Verlag KG Stuttgart · New York

Antioxidant Lignans from Mananthes patentiflora

Junmian Tian1 , 2 , Xianwen Yang2 , Yingtong Di1 , Yanlin Ma3 , Ling Li3 , Lin Li1 , Hongping He1 , Xiaojiang Hao1
  • 1State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, P. R. China.
  • 2Department of Natural Product Chemistry, School of Pharmacy, Second Military Medical University, Shanghai, P. R. China
  • 3Yunnan Pharmacological Laboratories of Natural Products, Kunming Medical College, Kunming, P. R. China
Further Information

Publication History

received April 13, 2007 revised September 13, 2007

accepted November 14, 2007

Publication Date:
13 February 2009 (online)

    Permissions and Reprints

Abstract

A new tetrahydrofuranoketone lignan (1) and two new tetrahydrofuranoketone lignan glycosides (2, 3) were isolated from the ethanol extract of the aerial part of Mananthes patentiflora. The structure elucidations of these compounds were mainly established on the basis of 1D, 2D NMR and HR-mass spectroscopic analysis. All three compounds revealed potent antioxidant activities within the concentration range tested (0.08–50.0 µM).

Key words

Mananthes patentiflora - Acanthaceae - tetrahydrofuranoketone lignans - antioxidant activity

References

  • 1 Patrice A M, Massuo J K, Norman G L. (+)-Episesaminone, a Sesamum indicum furofuran lignan. Isolation and hemisynthesis.  J Nat Prod. 1997;  60 1189-1192
    CrossrefPubMedGoogle Scholar
  • 2 Chenchugari S, Karumanchi V R, Gottumukkala V S. Flavonoids, triterpenoids and a lignan from Vitex altissima.  Phytochemistry. 2005;  66 1707-1712
    CrossrefPubMedGoogle Scholar
  • 3 Yu H S, Chen C C, Shieh B J. Two new constituents from the leaves of Magnolia coco.  J Nat Prod. 1998;  61 1017-1019
    CrossrefPubMedGoogle Scholar
  • 4 Jung K Y, Kim D S, Oh S R, Park S H, Lee I S, Lee J J, Shin D H, Lee H K. Magnone A and B, novel anti-PAF tetrahydrofuran lignans from the flower buds of Magnolia fargesii.  J Nat Prod. 1998;  61 808-811
    CrossrefPubMedGoogle Scholar
  • 5 Andrew T M, Maioli L C, Bruce M F, Dana M G. Asymmetric synthesis of sesaminone: confirmation of its structure and determination of its absolute configuration.  J Org Chem. 1997;  62 7413-7417
    CrossrefPubMedGoogle Scholar
  • 6 Li N, Jia A Q, Liu Y Q, Zhou J. Two new cycloartane-type triterpene glycosides from Curculigo orchioides.  Acta Bot Yunn. 2003;  25 241-244
    PubMedGoogle Scholar
  • 7 Ghada S N, Musa H AZ, Salim S S, Dawud M AE. Chemical constituents of the flora of Jordan, part III. Mono-O-acetyl diphyllin apioside, a new arylnaphthalene lignan from Haplophyllum buxaumii.  J Nat Prod. 1987;  50 748-750
    CrossrefPubMedGoogle Scholar
  • 8 Giuma M S, Karima M AA. Lignans of Haplophyllum tuberculatum.  Phytochemistry. 1984;  23 151-153
    CrossrefPubMedGoogle Scholar
  • 9 Sang B K, Ju Y B, Bo Y L, Yeon H S. Protective effects of fangchinoline and tetrandrine on hydrogen peroxide-induced oxidative neuronal cell damage in culture rat cerebellar granule cells.  Planta Med. 2003;  69 506-512
    Article in Thieme ConnectPubMedGoogle Scholar
  • 10 Yang X W, Zhao P J, Ma Y L, Xiao H T, Zuo Y Q, He H P, Li L, Hao X J. Mixed lignan-neolignans from Tarenna attenuata.  J Nat Prod. 2007;  70 521-525
    CrossrefPubMedGoogle Scholar

Dr. Hongping He

State Key Laboratory of Phytochemistry and Plant Resources in West China
Kunming Institute of Botany
Chinese Academy of Sciences

Kunming 650204

People's Republic of China

Phone: + 86 87 15 22 32 63

Fax: + 86 87 15 21 96 84

Email: hehongping@mail.kib.ac.cn

    www.thieme-connect.de/ejournals/toc/plantamedica
>