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Planta Med 2009; 75(13): 1436-1441
DOI: 10.1055/s-0029-1185726
Natural Product Chemistry
Original Paper
© Georg Thieme Verlag KG Stuttgart · New York

Diterpenoids from Casearia sylvestris

Wei Wang1 , Jianpin Zhao1 , Yan-hong Wang1 , Troy A. Smillie1 , Xing-Cong Li1 , Ikhlas A. Khan1 , 2
  • 1National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, University of Mississippi, Oxford, MS, USA
  • 2Department of Pharmacognosy, School of Pharmacy, University of Mississippi, Oxford, MS, USA
Further Information

Publication History

received January 21, 2009 revised April 4, 2009

accepted April 21, 2009

Publication Date:
14 May 2009 (online)

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Abstract

Two highly oxygenated clerodane diterpenes casearins U (1) and V (2) and two ent-kaurane diterpene glucosides sylvestrisides A (3) and B (4) were isolated from the leaves of Casearia sylvestris, together with 13 known compounds. Their structures were established on the basis of 1D and 2D NMR spectroscopic analyses and comparison with literature data.

Key words

Casearia sylvestris - Flacourtiaceae - clerodane diterpenes - ent‐kaurane diterpene glucosides - casearins U and V - sylvestrisides A and B

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Prof. Dr. Ikhlas A. Khan

National Center for Natural Products Research
School of Pharmacy
University of Mississippi

University Street

Oxford, MS 38677

USA

Phone: + 1 66 29 15 78 21

Fax: + 1 66 29 15 79 89

Email: ikhan@olemiss.edu

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