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Synfacts 2009(8): 0834-0834  
DOI: 10.1055/s-0029-1217456
Synthesis of Heterocycles
© Georg Thieme Verlag Stuttgart ˙ New York

Three-Component Synthesis of Benzothiazines

Contributor(s): Victor Snieckus, Johnathan Board
M. M. Heravi*, B. Baghernejad, H. A. Oskooie
Azzahra University, Tehran, Iran
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Publication History

Publication Date:
23 July 2009 (online)

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Significance

Reported is a synthesis of benzo[1,4]thiazines by a three-component reaction of aromatic aldehydes, isocyanides and o-amino­thiophenols. The yields of the reactions are excellent and the procedure is very simple involving no chromatography.