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Synfacts 2009(11): 1224-1224  
DOI: 10.1055/s-0029-1218086
Synthesis of Materials and Unnatural Products
© Georg Thieme Verlag Stuttgart ˙ New York

Hooping it up

Contributor(s): Timothy M. Swager, Jason R. Cox
H. Takaba, H. Omachi, Y. Yamamoto, J. Bouffard, K. Itami*
Nagoya University, Japan
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Publication History

Publication Date:
22 October 2009 (online)

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Significance

The authors describe a selective synthesis of the macrocyclic compound [12]cycloparaphenylene. The authors recognized that the strain energy of the resulting nanohoop (55 kcal mol-¹) would preclude a macrocyclization route using oligoparaphenylene. Instead, the cyclization is carried out using cyclohexane derivatives as templates.