Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000131.xml
Synfacts 2010(1): 0105-0105
DOI: 10.1055/s-0029-1218490
DOI: 10.1055/s-0029-1218490
Organo- and Biocatalysis
© Georg Thieme Verlag
Stuttgart ˙ New York
Combining Gold- and Organocatalysis
S. Belot, K. A. Vogt, C. Besnard, N. Krause*, A. Alexakis*
Université de Genevé, Switzerland and Technische Universität Dortmund, Germany
Further Information
Publication History
Publication Date:
21 December 2009 (online)
Significance
A one-pot enantioselective organocatalytic Michael addition of aldehydes to nitroenynes and subsequent gold-catalyzed cyclo-acetalization is presented. This process provides the products in high yields with excellent diastereoselectivities and high enantioselectivities.