Dtsch Med Wochenschr 2009; 134: S136-S139
DOI: 10.1055/s-0029-1222590
Kurzübersicht | Review article
Pharmakotherapie, Schlafmedizin
© Georg Thieme Verlag KG Stuttgart · New York

Optimierung der Galenik von Analgetika zur Behandlung chronischer Schmerzzustände

Mögliche Auswirkungen auf SchlafstörungenOptimizing the galenical formulation of analgetics for the treatment of chronic pain conditionsPossible effects on sleep disordersH. Blume1
  • 1SocraTec Research & Development GmbH, Oberursel
Further Information

Publication History

eingereicht: 11.11.2008

akzeptiert: 24.04.2009

Publication Date:
24 June 2009 (online)

Literatur

  • 1 Ackerman S J, Mordin M, Reblando J. et al . Patient-reported utilization patterns of fentanyl transdermal system and oxycodone hydrochloride controlled-release among patients with chronic nonmalignant pain.  J Manag Care Pharm. 2003;  9 223-231
  • 2 Drover D R, Angst M S, Valle M. et al . Input characteristics and bioavailability after administration of immediate and a new extended-release formulation of hydromorphone in healthy volunteers.  Anesthesiology. 2002;  97 827-836
  • 3 Gallagher R M, Welz-Bosna M, Gammaitoni A. Assessment of dosing frequency of sustained-release opioid preparations in patients with chronic nonmalignant pain.  Pain Med. 2007;  8 71-74
  • 4 Grond S, Radbruch L, Lehmann K A. Clinical pharmacokinetics of transdermal opioids: focus on transdermal fentanyl.  Clin Pharmacokinet. 2000;  38 59-89
  • 5 Miaskowski C. Pharmacologic management of sleep disturbances in noncancer-related pain.  Pain Management Nursing. 2008; 
  • 6 Palangio M, Northfelt D W, Portenoy R K. et al . Dose conversion and titration with a novel, once-daily, OROS® osmotic technology, extended-release hydromorphone formulation in the treatment of chronic malignant or nonmalignant pain.  J Pain Symptom Manage. 2002;  23 355-368
  • 7 Radbruch L, Sabatowski R, Petzke F. et al . Transdermal fentanyl for the management of cancer pain: a survey of 1005 patients.  Palliat Med. 2001;  15 309-321
  • 8 Sathyan G, Guo C, Sivakumar K. et al . Evaluation of the bioequivalence of two transdermal fentanyl systems following single and repeat applications.  Current Medical Research and Opinion. 2005;  21 1961-1968
  • 9 Turk D C, Dworkin R H, Revicki D. et al . Identifying important outcome domains for chronic pain clinical trials: An IMMPACT survey of people with pain.  Pain. 2008;  137 276-285
  • 10 Visionenfür eine optimierte Opioidtherapie – 12. SocraTec Expertengespräch.  Deutsche Apotheker Zeitung (DAZ). 2007;  147 49-50
  • 11 World Health Organisation .Cancer pain release appraising the Who Analgesic Ladder on its 20th anniversary. Geneve; WHO 2006
  • 12 Wonnemann M, Schug B, Schmücker K. et al . Significant food interactions observed with a nifedipine modified-release formulation marketed in the European Union.  Intern J Clin Pharmacol Therapeut. 2006;  44 38-48
  • 13 Wonnemann M, Schug B, Anschütz M. et al . Comparison of two marketed nifedipine modified-release formulation: An exploratory clinical food interaction study.  Clin Therapeutics. 2008;  30 1-11

Prof. Dr. Henning Blume

SocraTec Research & Development GmbH

Im Setzling 35

61440 Oberursel

Phone: 06171/58571-20

Fax: 06171/5857-25

Email: henning.blume@socratec-pharma.de

    >