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Dtsch Med Wochenschr 2009; 134(33): 1635-1640
DOI: 10.1055/s-0029-1233993
CME-Beitrag | Review article
Gastroenterologie, Rheumatologie
© Georg Thieme Verlag KG Stuttgart ·New York

Nichtsteroidale Antirheumatika (NSAR) – an der Schnittstelle gastrointestinaler Nebenwirkungen und kardiovaskulärer Risiken

Non steroidal anti-inflammatory drugs (NSAIDs) – balancing gastrointestinal complications and the cardiovascular riskA. Kandulski1 , M. Venerito1 , P. Malfertheiner1
  • 1Klinik für Gastroenterologie, Hepatologie und Infektiologie, Otto-von-Guericke Universität Magdeburg
Further Information

Publication History

eingereicht: 13.5.2009

akzeptiert: 23.7.2009

Publication Date:
31 July 2009 (online)

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Zusammenfassung

Nicht-steroidale Antirheumatika (NSAR) gehören aufgrund ihrer anti-inflammatorischen, analgetischen und antipyretischen Eigenschaften nicht nur im Fachbereich der Rheumatologie zu den am häufigsten verordneten Substanzen. Bei der Ko-Medikation von NSAR sind sowohl gastrointestinale Nebenwirkungen als auch zerebro- und kardiovaskuläre Komplikationen zu berücksichtigen und das individuelle Risiko des einzelnen Patienten vor Beginn einer Therapie genau definieren.

Summary

Because of their anti-inflammatory, analgesic and antipyretic properties non-steroidal anti-inflammatory drugs (NSAIDs) are among the most frequently prescribed throughout all medical fields. Both gastrointestinal as well as cerebro- and cardiovascular risk needs to be considered. Especially before starting a long-term medical treatment with NSAIDs the individual gastrointestinal and cardiovascular risk of the patient has to be assessed carefully.

Schlüsselwörter

NSAR - kardiovaskuläres Risiko - gastrointestinale Blutung

Keywords

NSAIDs - cardiovascular risk - gastrointestinal bleeding

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Prof. Dr. med. Peter Malfertheiner

Klinik für Gastroenterologie, Hepatologie und Infektiologie, Otto-von-Guericke Universität Magdeburg

Leipziger Str. 44

Phone: 0391/6713100

Email: Peter.Malfertheiner@med.ovgu.de

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