Dtsch Med Wochenschr 2009; 134(37): 1835-1837
DOI: 10.1055/s-0029-1237522
Kommentar | Commentary
Gastroenterologie, Onkologie
© Georg Thieme Verlag KG Stuttgart · New York

Neoadjuvante Therapien bei gastrointestinalen Tumoren: Müssen wir umdenken?

The neoadjuvant treatment of gastrointestinal tumors: time for rethinking?M. P. Ebert1 , R. M. Schmid1
  • 1II. Medizinische Klinik des Klinikums rechts der Isar, Technische Universität München
Further Information

Publication History

eingereicht: 10.5.2009

akzeptiert: 23.7.2009

Publication Date:
02 September 2009 (online)

Literatur

  • 1 Bedenne L, Michel P, Bouché O. et al . Chemoradiation followed by surgery compared with chemoradiation alone in squamous cancer of the esophagus: FFCD 9102.  J Clin Oncol. 2007;  25 1160-1168
  • 2 Boige V, Pignon J, Saint-Aubert B. et al . Final results of a randomized trial comparing preoperative 5-fluorouracil (F)/cisplatin (P) to surgery alone in adenocarcinoma of stomach and lower esophagus (ASLE).  J Clin Oncol. 2007;  25 18S
  • 3 Bosset J F, Gignoux M, Triboulet J P. et al . Chemoradiotherapy followed by surgery compared with surgery alone in squamous-cell cancer of the esophagus.  N Engl J Med. 1997;  337 161-167
  • 4 Burmeister B H, Smithers B M, Gebski V. et al . Surgery alone versus chemoradiotherapy followed by surgery for resectable cancer of the oesophagus.  Lancet Oncol. 2005;  6 659-668
  • 5 Chauffert B, Mornex F, Bonnetain F. et al . Phase III trial comparing intensive induction chemoradiotherapy (60 Gy, infusional 5-FU and intermittent cisplatin) followed by maintenance gemcitabine with gemcitabine alone for locally advanced unresectable pancreatic cancer.  Ann Oncol. 2008;  19 1592-1599
  • 6 Cunningham D, Allum W H, Stenning S P. et al . Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer.  N Engl J Med. 2006;  355 11-20
  • 7 Imamura M, Doi R, Imaizumi T. et al . A randomized multicenter trial comparing resection and radiochemotherapy for resectable locally invasive pancreatic cancer.  Surgery. 2004;  136 1003-1011
  • 8 Palmer D H, Stocken D D, Hewitt H. et al . A randomized phase 2 trial of neoadjuvant chemotherapy in resectable pancreatic cancer: gemcitabine alone versus gemcitabine combined with cisplatin.  Ann Surg Oncol. 2007;  14 2088-2096
  • 9 Sauer R, Becker H, Hohenberger W. et al . Preoperative versus postoperative chemoradiotherapy for rectal cancer.  N Engl J Med. 2004;  351 1731-1740
  • 10 Stahl M, Stuschke M, Lehmann N. et al . Chemoradiation with and without surgery in patients with locally advanced squamous cell carcinoma of the esophagus.  J Clin Oncol. 2005;  23 2310-2317
  • 11 Stahl M, Walz M K, Stuschke M. et al . Phase III comparison of preoperative chemotherapy compared with chemoradiotherapy in patients with locally advanced adenocarcinoma of the esophagogastric junction.  J Clin Oncol. 2009;  27 851-856
  • 12 Witzigmann H, Berr F, Ringel U. et al . Surgical and palliative management and outcome in 184 patients with hilar cholangiocarcinoma.  Ann Surg. 2006;  244 230-239

Prof. Dr. M. Ebert

II. Medizinische Klinik des Klinikums rechts der Isar, Technische Universität München

Ismaninger Str. 22

81675 München

Phone: 089/4140-4386

Fax: 089/4140-4115

Email: Matthias.Ebert@lrz.tum.de

    >