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Dtsch Med Wochenschr 2010; 135(6): 256-259
DOI: 10.1055/s-0030-1247864
DOI: 10.1055/s-0030-1247864
Arzneimittel & Pharmakotherapie | Review
article
Angiologie
© Georg Thieme Verlag KG Stuttgart · New York
Dabigatran: eine neue Option zur Therapie und Prophylaxe thrombembolischer Erkrankungen?
Dabigatran: a new therapeutic option for therapy and prophylaxis of thromboembolic diseases?Further Information
Publication History
eingereicht: 27.8.2009
akzeptiert: 26.11.2009
Publication Date:
26 January 2010 (online)
Schlüsselwörter
Dabigatran - Thrombose - direkter Thrombininhibitor
Keywords
dabigatran - thrombosis - direct thrombin inhibitor
Literatur
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- 10 Liesenfeld K H, Schafer H G, Troconiz I F, Tillmann C, Eriksson B I, Stangier J. Effects of the direct thrombin inhibitor dabigatran on ex vivo coagulation time in orthopaedic surgery patients: a population model analysis. Br J Clin Pharmacol. 2006; 62 527-537
- 11 Stangier J, Eriksson B I, Dahl O E, Ahnfelt L, Nehmiz G, Stahle H, Rathgen K, Svard R. Pharmacokinetic profile of the oral direct thrombin inhibitor dabigatran etexilate in healthy volunteers and patients undergoing total hip replacement. J Clin Pharmacol. 2005; 45 555-563
- 12 Stangier J, Rathgen K, Stahle H, Gansser D, Roth W. The pharmacokinetics, pharmacodynamics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor, in healthy male subjects. Br J Clin Pharmacol. 2007; 64 292-303
Dr. Natig Gassanov
Herzzentrum Köln, Klinik III für
Innere Medizin
Kerpener Str. 62
50924 Köln
Phone: 0221/47832544
Email: Natig.Gassanov@uk-koeln.de