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Synfacts 2010(9): 0993-0993
DOI: 10.1055/s-0030-1258013
DOI: 10.1055/s-0030-1258013
Synthesis of Heterocycles
© Georg Thieme Verlag
Stuttgart ˙ New York
Concerning the Regioselectivity of the Hurd-Mori Reaction for 1,2,3-Thiadiazoles
M. Turner, T. Linder, M. Schnürch, M. D. Mihovilovic*, P. Stanetty
Vienna University of Technology, Austria
Further Information
Publication History
Publication Date:
23 August 2010 (online)
Significance
The work investigates the regioselectivity of the Hurd-Mori reaction on 1,2,3-thiadiazoles. The success of the described cyclization events is found to be highly dependant on the presence of an electron-withdrawing group. Steric factors are highlighted as critical in the regioselectivity of the process.