Synthesis of Functionalized
Benzofurans by a Double Heck Reaction of 2,3-Dibromofurans
and Subsequent 6π-Electrocyclization/Dehydrogenation

Ghazwan Ali Salman; Asad Ali; Munawar Hussain; Rasheed Ahmad Khera; Peter Langer

doi:10.1055/s-0030-1260666

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Synthesis 2011(14): 2208-2214
DOI: 10.1055/s-0030-1260666

SPECIALTOPIC

Synthesis of Functionalized Benzofurans by a Double Heck Reaction of 2,3-Dibromofurans and Subsequent 6π-Electrocyclization/Dehydrogenation

Ghazwan Ali Salman^a, Asad Ali^a,b, Munawar Hussain^a, Rasheed Ahmad Khera^a,c, Peter Langer*^a,d
^a Institut für Chemie, Universität Rostock, Albert-Einstein-Str. 3a, 18059 Rostock, Germany
^b Department of Chemistry, University of Mardan, Mardan, Pakistan
^c Department of Chemistry, University Faisalabad, Government College, Faisalabad, Pakistan
^d Leibniz-Institut für Katalyse an der Universität Rostock e.V., Albert-Einstein-Str. 29a, 18059 Rostock, Germany
Fax: +49(381)4986412; e-Mail: peter.langer@uni-rostock.de;

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Publication History

Received 14 March 2011
Publication Date:
09 June 2011 (online)

Abstract
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Abstract

The twofold Heck reaction of 2,3-dibromofurans afforded 2,3-di(alkenyl)furans which were transformed into functionalized benzofurans by a domino 6π-electrocyclization/dehydrogenation reaction.

Key words

catalysis - palladium - Heck reaction - electrocyclization - furans

References

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