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Synfacts 2011(10): 1114-1114
DOI: 10.1055/s-0030-1261070
DOI: 10.1055/s-0030-1261070
Metal-Mediated Synthesis
© Georg Thieme Verlag
Stuttgart ˙ New York
Ni-Catalyzed Cross-Coupling of Aryl Halides with Diphenylphosphine Oxide
X. Zhang, H. Liu, X. Hu, G. Tang*, J. Zhu*, Y. Zhao
Xiamen University and Tsinghua University, Beijing, P. R. of China
Further Information
Publication History
Publication Date:
20 September 2011 (online)
Significance
A new nickel-catalyzed method for the cross-coupling of various aryl halides with diphenylphosphine oxide is described. The reaction can be performed under air in water with zinc powder as reducing agent and 2,2′-bipyridine as ligand.