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J Neurol Surg B Skull Base 2012; 73(05): 302-307
DOI: 10.1055/s-0032-1321506
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

New Dried Human Amniotic Membrane Is Useful as a Substitute for Dural Repair after Skull Base Surgery

Takahiro Tomita
1   Departments of Neurosurgery, University of Toyama Graduate School of Medicine and Pharmaceutical Sciences, Toyama, Japan
,
Nakamasa Hayashi
1   Departments of Neurosurgery, University of Toyama Graduate School of Medicine and Pharmaceutical Sciences, Toyama, Japan
,
Motonori Okabe
2   Departments of Regenerative Medicine, University of Toyama Graduate School of Medicine and Pharmaceutical Sciences, Toyama, Japan
,
Toshiko Yoshida
2   Departments of Regenerative Medicine, University of Toyama Graduate School of Medicine and Pharmaceutical Sciences, Toyama, Japan
,
Hideo Hamada
1   Departments of Neurosurgery, University of Toyama Graduate School of Medicine and Pharmaceutical Sciences, Toyama, Japan
,
Shunro Endo
1   Departments of Neurosurgery, University of Toyama Graduate School of Medicine and Pharmaceutical Sciences, Toyama, Japan
,
Toshio Nikaido
2   Departments of Regenerative Medicine, University of Toyama Graduate School of Medicine and Pharmaceutical Sciences, Toyama, Japan
› Author Affiliations
Further Information

Publication History

12 January 2011

25 April 2011

Publication Date:
30 July 2012 (online)

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Abstract

Objectives Cerebrospinal fluid (CSF) leakage is an undesirable complication of skull base surgery. We used dried human amniotic membrane (AM) as a patch graft for dural repair to determine its efficacy in preventing CSF leakage.

Design Frontoparietal craniotomy and removal of dura were performed in 20 Wistar rats. A dried AM was placed to cover the dural defect without suturing in 16 animals. In four animals, an expanded polytetrafluoroethylene was implanted. At 2 weeks and 1, 3, and 6 months, histological examination was performed. Dried AM was also used as a substitute in 10 patients who underwent skull base surgery, after approval by the Ethics Committee of the University of Toyama.

Results At 2 weeks after implantation, thick connective tissue completely enclosed the dried AM. At 1 month after implantation, the connective tissue became thin and the implanted AM shortened. At 3 and 6 months after implantation, histological examination revealed disappearance of the dried AM and formation of membranous tissue. In the clinical study, neither CSF leakage nor clinical adverse reactions directly related to the dried AM were observed.

Conclusion Dried human AM appears to be an ideal substitute for dura, since it is replaced by natural tissue.

Keywords

amniotic membrane - cerebrospinal fluid (CSF) leakage - dural repair - dural substitute - skull base surgery
 

  • References

  • 1 Parízek J, Mĕricka P, Husek Z , et al. Detailed evaluation of 2959 allogeneic and xenogeneic dense connective tissue grafts (fascia lata, pericardium, and dura mater) used in the course of 20 years for duraplasty in neurosurgery. Acta Neurochir (Wien) 1997; 139: 827-838
    CrossrefPubMedGoogle Scholar
  • 2 Masullo C, Pocchiari M, Macchi G, Alema G, Piazza G, Panzera MA. Transmission of Creutzfeldt-Jakob disease by dural cadaveric graft. J Neurosurg 1989; 71: 954-955
    PubMedGoogle Scholar
  • 3 Thadani V, Penar PL, Partington J , et al. Creutzfeldt-Jakob disease probably acquired from a cadaveric dura mater graft. Case report. J Neurosurg 1988; 69: 766-769
    CrossrefPubMedGoogle Scholar
  • 4 Cohen AR, Aleksic S, Ransohoff J. Inflammatory reaction to synthetic dural substitute. Case report. J Neurosurg 1989; 70: 633-635
    CrossrefPubMedGoogle Scholar
  • 5 Simpson D, Robson A. Recurrent subarachnoid bleeding in association with dural substitute. Report of three cases. J Neurosurg 1984; 60: 408-409
    CrossrefPubMedGoogle Scholar
  • 6 Thompson DN, Taylor WF, Hayward RD. Silastic dural substitute: experience of its use in spinal and foramen magnum surgery. Br J Neurosurg 1994; 8: 157-167
    CrossrefPubMedGoogle Scholar
  • 7 Toda A, Okabe M, Yoshida T, Nikaido T. The potential of amniotic membrane/amnion-derived cells for regeneration of various tissues. J Pharmacol Sci 2007; 105: 215-228
    CrossrefPubMedGoogle Scholar
  • 8 Kitagawa K, Yanagisawa S, Watanabe K , et al. A hyperdry amniotic membrane patch using a tissue adhesive for corneal perforations and bleb leaks. Am J Ophthalmol 2009; 148: 383-389
    CrossrefPubMedGoogle Scholar
  • 9 Macfarlane MR, Symon L. Lyophilised dura mater: experimental implantation and extended clinical neurosurgical use. J Neurol Neurosurg Psychiatry 1979; 42: 854-858
    CrossrefPubMedGoogle Scholar
  • 10 Narotam PK, van Dellen JR, Bhoola KD. A clinicopathological study of collagen sponge as a dural graft in neurosurgery. J Neurosurg 1995; 82: 406-412
    CrossrefPubMedGoogle Scholar
  • 11 Narotam PK, Qiao F, Nathoo N. Collagen matrix duraplasty for posterior fossa surgery: evaluation of surgical technique in 52 adult patients. Clinical article. J Neurosurg 2009; 111: 380-386
    CrossrefPubMedGoogle Scholar
  • 12 Stendel R, Danne M, Fiss I , et al. Efficacy and safety of a collagen matrix for cranial and spinal dural reconstruction using different fixation techniques. J Neurosurg 2008; 109: 215-221
    CrossrefPubMedGoogle Scholar
  • 13 Yamagata S, Goto K, Oda Y, Kikuchi H. Clinical experience with expanded polytetrafluoroethylene sheet used as an artificial dura mater. Neurol Med Chir (Tokyo) 1993; 33: 582-585
    CrossrefPubMedGoogle Scholar
  • 14 Yamada K, Miyamoto S, Nagata I , et al. Development of a dural substitute from synthetic bioabsorbable polymers. J Neurosurg 1997; 86: 1012-1017
    CrossrefPubMedGoogle Scholar
  • 15 Yamada K, Miyamoto S, Takayama M , et al. Clinical application of a new bioabsorbable artificial dura mater. J Neurosurg 2002; 96: 731-735
    CrossrefPubMedGoogle Scholar
  • 16 Narotam PK, Van Dellen JR, Bhoola K, Raidoo D. Experimental evaluation of collagen sponge as a dural graft. Br J Neurosurg 1993; 7: 635-641
    CrossrefPubMedGoogle Scholar
  • 17 McCall TD, Fults DW, Schmidt RH. Use of resorbable collagen dural substitutes in the presence of cranial and spinal infections-report of 3 cases. Surg Neurol 2008; 70: 92-96 , discussion 96–97
    CrossrefPubMedGoogle Scholar
  • 18 Pettorini BL, Tamburrini G, Massimi L, Paternoster G, Caldarelli M, Di Rocco C. The use of a reconstituted collagen foil dura mater substitute in paediatric neurosurgical procedures—experience in 47 patients. Br J Neurosurg 2010; 24: 51-54
    CrossrefPubMedGoogle Scholar
  • 19 Adinolfi M, Akle CA, McColl I , et al. Expression of HLA antigens, beta 2-microglobulin and enzymes by human amniotic epithelial cells. Nature 1982; 295: 325-327
    CrossrefPubMedGoogle Scholar
  • 20 Akle CA, Adinolfi M, Welsh KI, Leibowitz S, McColl I. Immunogenicity of human amniotic epithelial cells after transplantation into volunteers. Lancet 1981; 2: 1003-1005
    PubMedGoogle Scholar
  • 21 Hammer A, Hutter H, Blaschitz A , et al. Amnion epithelial cells, in contrast to trophoblast cells, express all classical HLA class I molecules together with HLA-G. Am J Reprod Immunol 1997; 37: 161-171
    CrossrefPubMedGoogle Scholar
  • 22 Hao Y, Ma DH, Hwang DG, Kim WS, Zhang F. Identification of antiangiogenic and antiinflammatory proteins in human amniotic membrane. Cornea 2000; 19: 348-352
    CrossrefPubMedGoogle Scholar
  • 23 Kamiya K, Wang M, Uchida S , et al. Topical application of culture supernatant from human amniotic epithelial cells suppresses inflammatory reactions in cornea. Exp Eye Res 2005; 80: 671-679
    CrossrefPubMedGoogle Scholar
  • 24 Kubo M, Sonoda Y, Muramatsu R, Usui M. Immunogenicity of human amniotic membrane in experimental xenotransplantation. Invest Ophthalmol Vis Sci 2001; 42: 1539-1546
    PubMedGoogle Scholar
  • 25 Li H, Niederkorn JY, Neelam S , et al. Immunosuppressive factors secreted by human amniotic epithelial cells. Invest Ophthalmol Vis Sci 2005; 46: 900-907
    CrossrefPubMedGoogle Scholar
  • 26 Solomon A, Rosenblatt M, Monroy D, Ji Z, Pflugfelder SC, Tseng SCG. Suppression of interleukin 1 alpha and interleukin 1 beta in human limbal epitherial cells cultured on the amnotiv membrane stromal matrix. Br J Ophthalmol 2001; 85: 444-449
    CrossrefPubMedGoogle Scholar
  • 27 Talmi YP, Sigler L, Inge E, Finkelstein Y, Zohar Y. Antibacterial properties of human amniotic membranes. Placenta 1991; 12: 285-288
    CrossrefPubMedGoogle Scholar
  • 28 Tseng SCG, Li DQ, Ma X. Suppression of transforming growth factor-beta isoforms, TGF-beta receptor type II, and myofibroblast differentiation in cultured human corneal and limbal fibroblasts by amniotic membrane matrix. J Cell Physiol 1999; 179: 325-335
    CrossrefPubMedGoogle Scholar
  • 29 Sakuragawa N, Yoshikawa H, Sasaki M. Amniotic tissue transplantation: clinical and biochemical evaluations for some lysosomal storage diseases. Brain Dev 1992; 14: 7-11
    CrossrefPubMedGoogle Scholar
  • 30 Scaggiante B, Pineschi A, Sustersich M, Andolina M, Agosti E, Romeo D. Successful therapy of Niemann-Pick disease by implantation of human amniotic membrane. Transplantation 1987; 44: 59-61
    CrossrefPubMedGoogle Scholar
  • 31 Burman S, Tejwani S, Vemuganti GK, Gopinathan U, Sangwan VS. Ophthalmic applications of preserved human amniotic membrane: a review of current indications. Cell Tissue Bank 2004; 5: 161-175
    CrossrefPubMedGoogle Scholar
  • 32 Gibbs Jr CJ, Gajdusek DC, Latarjet R. Unusual resistance to ionizing radiation of the viruses of kuru, Creutzfeldt-Jakob disease, and scrapie. Proc Natl Acad Sci U S A 1978; 75: 6268-6270
    CrossrefPubMedGoogle Scholar
  • 33 Becker SS, Jackler RK, Pitts LH. Cerebrospinal fluid leak after acoustic neuroma surgery: a comparison of the translabyrinthine, middle fossa, and retrosigmoid approaches. Otol Neurotol 2003; 24: 107-112
    CrossrefPubMedGoogle Scholar
  • 34 Ganly I, Patel SG, Singh B , et al. Complications of craniofacial resection for malignant tumors of the skull base: report of an international collaborative study. Head Neck 2005; 27: 445-451
    CrossrefPubMedGoogle Scholar
  • 35 Leonetti JP, Anderson D, Marzo S, Moynihan G. Prevention and management of cerebrospinal fluid fistula after transtemporal skull base surgery. Skull Base 2001; 11: 87-92
    Article in Thieme ConnectPubMedGoogle Scholar
  • 36 Mangham CA. Complications of translabyrinthine vs. suboccipital approach for acoustic tumor surgery. Otolaryngol Head Neck Surg 1988; 99: 396-400
    PubMedGoogle Scholar
  • 37 Sen C, Snderman CH, Sekhar LN. Complications of skull base operation. In: Sekhar LN, Janacka IP, eds. Surgery of Cranial Base Tumors. New York: Rave Press; 1993: 831-839
    Google Scholar
  • 38 Hakuba A, Nishimura S, Jang BJ. A combined retroauricular and preauricular transpetrosal-transtentorial approach to clivus meningiomas. Surg Neurol 1988; 30: 108-116
    Google Scholar
  • 39 Jackson IT, Adham MN, Marsh WR. Use of the galeal frontalis myofascial flap in craniofacial surgery. Plast Reconstr Surg 1986; 77: 905-910
    CrossrefPubMedGoogle Scholar
  • 40 Kryzanski JT, Annino DJ, Gopal H, Heilman CB. Low complication rates of cranial and craniofacial approaches to midline anterior skull base lesions. Skull Base 2008; 18: 229-241
    Article in Thieme ConnectPubMedGoogle Scholar