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Planta Med 2013; 79(09): 792-796
DOI: 10.1055/s-0032-1328537
Natural Product Chemistry
Letters
Georg Thieme Verlag KG Stuttgart · New York

Three New Xanthones from the Resin of Garcinia hanburyi

Yun-Xia Deng
1   School of Pharmacy, Fudan University, Shanghai, China
2   College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai, China
,
Tao Guo
3   School of Life and Engineering, Lanzhou University of Technology, Lanzhou, China
,
Zhi-Yu Shao
2   College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai, China
,
Hui Xie
1   School of Pharmacy, Fudan University, Shanghai, China
,
Sheng-Li Pan
1   School of Pharmacy, Fudan University, Shanghai, China
› Author Affiliations
Further Information

Publication History

received 05 January 2013
revised 20 March 2013

accepted 09 April 2013

Publication Date:
13 May 2013 (online)

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Abstract

Three new xanthones, 22,23-dihydroxydihydrogambogenic acid (1), 12-hydroxygambogefic acid A (2), and hanburixanthone (3), along with thirteen known compounds were isolated from the resin of Garcinia hanburyi. The structures of the new compounds were determined by detailed analysis of 1D and 2D NMR spectra and by comparison with related model compounds. All compounds were tested for their cytotoxicities against A549, HCT116, and MDA-MB-231, and most of them showed significant effects on the cell lines.

Key words

Garcinia hanburyi - Clusiaceae - xanthones - cytotoxicity

Supporting Information

 

  • References

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