Dtsch Med Wochenschr 2013; 138(10): 488-492
DOI: 10.1055/s-0032-1332900
Konsensus | Review article
Arbeitsmedizin
© Georg Thieme Verlag KG Stuttgart · New York

S3-Leitlinie Gesundheitsüberwachung bei Beryllium-Exposition und diagnostisches Vorgehen bei berylliumassoziierter Erkrankung

Health surveillance for workers exposed to beryllium and diagnostic procedures in beryllium-associated diseases
U. Euler
1   TU Dresden, Institut und Poliklinik für Arbeits- und Sozialmedizin
8   Bundesanstalt für Arbeitsschutz und Arbeitsmedizin, Berlin
,
D. Dahmann
2   Institut für Gefahrstoff-Forschung, Bochum
,
M. Follmann
3   Deutsche Krebsgesellschaft e. V.
,
K. I. Gaede
4   Forschungszentrum Borstel
,
A. Gäßler
5   Verband Deutscher Betriebs- und Werksärzte e. V, Karlsruhe
,
D. Groneberg
6   Goethe- Universität Frankfurt, Instituts für Arbeits-, Sozial- und Umweltmedizin
,
M. Heger
7   Landesamt für Umwelt- und Arbeitsschutz, Saarbrücken
,
K. Krutz
8   Bundesanstalt für Arbeitsschutz und Arbeitsmedizin, Berlin
,
U. Latza
8   Bundesanstalt für Arbeitsschutz und Arbeitsmedizin, Berlin
,
M. Lelgemann
9   Medizinischer Dienst des Spitzenverbandes Bund der Krankenkassen e.V., Essen
,
S. Letzel
10   Institut für Arbeits-, Sozial- und Umweltmedizin der Johannes Gutenberg-Universität Mainz
,
R. Merget
11   Institut für Prävention und Arbeitsmedizin der Deutschen gesetzlichen Unfallversicherung, Institut der Ruhr-Universität Bochum (IPA), Bochum
,
J. Müller-Quernheim
12   Universitätsklinikum Freiburg
,
T. Nauert
13   Landesamt für Gesundheit und Arbeitssicherheit, Kiel
,
A. Seidler
1   TU Dresden, Institut und Poliklinik für Arbeits- und Sozialmedizin
› Author Affiliations
Further Information

Publication History

Publication Date:
26 February 2013 (online)

 
  • Literatur

  • 1 Agency for Toxic Substances and Disease Registry. Toxicological Profile for Beryllium. Washington: U.S. Department of Health and Human Services; 2002
  • 2 Apostoli P, Schaller KH. Urinary beryllium – a suitable tool for assessing occupational and environmental beryllium exposure?. Int Arch Occup Environ Health 2001; 74: 162-166
  • 3 Domingo JL, Schuhmacher M, Agramunt MC et al. Levels of metals and organic substances in blood and urine of workers at a new hazardous waste incinerator. Int Arch Occup Environ Health 2001; 74: 263-269
  • 4 Frame GM, Ford RE, Scribner WG et al. Trace determination of beryllium oxide in biological samples by electron-capture gas chromatography. Anal Chem 1974; 46: 534-539
  • 5 Henneberger PK, Goe SK, Miller WE et al. Industries in the United States with airborne beryllium exposure and estimates of the number of current workers potentially exposed. J Occup Environ Hyg 2004; 1: 648-659
  • 6 Middleton D, Kowalski P. Advances in identifying beryllium sensitization and disease. Int J Environ Res Public Health 2010; 7: 115-124
  • 7 Middleton DC, Fink J, Kowalski PJ et al. Optimizing BeLPT criteria for beryllium sensitization. Am J Ind Med 2008; 51: 166-172
  • 8 Middleton DC, Lewin MD, Kowalski PJ et al. The BeLPT: algorithms and implications. Am J Ind Med 2006; 49: 36-44
  • 9 Muller-Quernheim J, Gaede KI, Fireman E et al. Diagnoses of chronic beryllium disease within cohorts of sarcoidosis patients. Eur Respir J 2006; 27: 1190-1195
  • 10 National Research Council. Health effects of beryllium exposure – a literature review. Washington: The National Academies Press; 2007. http://www.nap.edu/openbook.php?record_id=12007&page=R1
  • 11 National Research Council. Managing health effects of beryllium exposure. Washington: The National Academies Press; 2008. http://www.nap.edu/openbook.php?record_id=12464
  • 12 Paschal DC, Ting BG, Morrow JC et al. Trace metals in urine of United States residents: reference range concentrations. Environ Res 1998; 76: 53-59
  • 13 Pott GB, Palmer BE, Sullivan AK et al. Frequency of beryllium-specific, TH1-type cytokine-expressing CD4+ T cells in patients with beryllium-induced disease. J Allergy Clin Immunol 2005; 115: 1036-1042
  • 14 Rossman MD, Kern JA, Elias JA et al. Proliferative response of bronchoalveolar lymphocytes to beryllium. A test for chronic beryllium disease. Ann Intern Med 1988; 108: 687-693
  • 15 Sanderson WT, Ward EM, Steenland K et al. Lung cancer case-control study of beryllium workers. Am J Ind Med 2001; 39: 133-144
  • 16 Seidler A, Euler U, Müller-Quernheim J et al. Systematic review: progression of beryllium sensitization to chronic beryllium disease. Occup Med (Lond) 2012; 62: 506-513
  • 17 Stange AW, Furman FJ, Hilmas DE. The beryllium lymphocyte proliferation test: Relevant issues in beryllium health surveillance. Am J Ind Med 2004; 46: 453-462
  • 18 Stephan CH, Fournier M, Brousseau P et al. Graphite furnace atomic absorption spectrometry as a routine method for the quantification of beryllium in blood and serum. Chem Cent J 2008; 2: 14
  • 19 Stokes RF, Rossman MD. Blood cell proliferation response to beryllium: analysis by receiver-operating characteristics. J Occup Med 1991; 33: 23-28
  • 20 Taylor ML, Arnold EL. Ultratrace determination of metals in biological specimens quantitative determination of beryllium by gas cromatography. Anal Chem 1971; 42: 1328-1332
  • 21 Thomas CA, Bailey RL, Kent MS et al. Efficacy of a program to prevent beryllium sensitization among new employees at a copper-beryllium alloy processing facility. Public Health Rep 2009; 124 (Suppl. 01) 112-124
  • 22 Valentine-Thon E, Muller K, Guzzi G et al. LTT-MELISA is clinically relevant for detecting and monitoring metal sensitivity. Neuro Endocrinol Lett 2006; 27 (Suppl. 01) 17-24
  • 23 Vincent R, Catani J, Creau Y et al. Occupational exposure to beryllium in French enterprises: a survey of airborne exposure and surface levels. Ann Occup Hyg 2009; 53: 363-372
  • 24 Williams WR, Williams WJ. Comparison of lymphocyte transformation and macrophage migration inhibition tests in the detection of beryllium hypersensitivity. J Clin Pathol 1982; 35: 684-687
  • 25 Yao JJ, Hu SY. A study of immunological indices for diagnosis of chronic berylliosis. Biomed Environ Sci 1989; 2: 318-324