Developments in the Synthesis of 1,2-Dihydropyridines

Abstract

This review provides a comprehensive compilation of available literature concerning the synthesis of 1,2-dihydropyridines. The most important recent developments and concepts re­lated to this topic are emphasised.

1 Introduction

2 Synthesis of 1,2-Dihydropyridines

2.1 Condensation Reactions

2.2 Reduction of Pyridines and Pyridinium Salts

2.3 Nucleophilic Addition to Pyridines and Pyridinium Salts

2.4 Pericyclic Reactions

2.5 Other Methods

3 Conclusions

Key words

dihydropyridines - NADH - isoquinuclidines - pericyclic reactions - heterocyclic compounds

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