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Synthesis 2015; 47(20): 3231-3240
DOI: 10.1055/s-0034-1378854
DOI: 10.1055/s-0034-1378854
paper
A Magnesium-Based Diastereoselective Preparation of Pyridylic 1,3-Amino Alcohols Using the tert-Butyl Sulfinamide Auxiliary
Further Information
Publication History
Received: 30 April 2015
Accepted after revision: 26 May 2015
Publication Date:
22 July 2015 (online)
Abstract
1,3-Amino alcohols were prepared by using a two-step approach and an interesting reversal in diastereoselectivity is discussed.
Key words
organometallic addition - diastereoselectivity - sulfinamides - halogen-metal exchange - amino alcoholSupporting Information
- Supporting information for this article is available online at http://dx.doi.org/10.1055/s-0034-1378854.
- Supporting Information
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