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Synthesis 2016; 48(04): 573-578
DOI: 10.1055/s-0035-1560544
DOI: 10.1055/s-0035-1560544
paper
N-Heterocyclic Carbene Catalyzed Monoacylation of Vicinal Diols
Further Information
Publication History
Received: 30 September 2015
Accepted after revision: 09 November 2015
Publication Date:
25 November 2015 (online)
Abstract
The N-heterocyclic carbene (NHC)-catalyzed monoacylation of vicinal diols is described. Monoacylated compounds of 1,2-, 1,3-, and 1,4-diols are obtained in good yields and selectivity under mild reaction conditions at ambient temperature.
Key words
N-heterocyclic carbene - organocatalyst - vicinal diol - monoselectivity - acylation - monoprotectionSupporting Information
- Supporting information for this article is available online at http://dx.doi.org/10.1055/s-0035-1560544.
- Supporting Information
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