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Synthesis 2017; 49(14): 3107-3111
DOI: 10.1055/s-0036-1589023
DOI: 10.1055/s-0036-1589023
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Synthesis and Resolution of a Chiral Diamine: 2,2′-(Propane-2,2-diyl)dipyrrolidine
Further Information
Publication History
Received: 24 March 2017
Accepted after revision: 07 April 2017
Publication Date:
18 May 2017 (online)
Abstract
A short and practical synthesis of a new chiral dipyrrolidine is presented. The three-step route includes a hydrogenation and a resolution with mandelic acid, which easily affords large quantities of the title compound.
Supporting Information
- Supporting information for this article is available online at https://doi.org /10.1055/s-0036-1589023.
- Supporting Information
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