Tobias Cronberg, MD, PhD, and Hans Friberg, MD, PhD, EDIC

The Guest Editors of this issue of Seminars in Neurology are Drs. Tobias Cronberg and Hans Friberg from Lund University, Sweden.

Dr. Cronberg is Associate Professor, Senior Consultant, and Adjunct Senior Lecturer in the Department of Neurology and Rehabilitation Medicine at Skane University Hospital in Lund. He received his MD from Lund University in 1991, and his PhD in 2004 in Experimental Brain Research, focusing on mechanisms of ischemic cell death in the central nervous system. He underwent neurology training at Skane University Hospital in Lund and is subspecialized in stroke and epilepsy. His research is focused on the treatment, diagnosis, and long-term consequences of cardiac arrest-induced brain injury. Dr. Cronberg was responsible for neurologic prognostication and follow-up in the Targeted Temperature Management after Cardiac Arrest (TTM) Trial and shares the senior investigator role for the TTM-2 Trial. He coordinated the Swedish guidelines on neuroprognostication after cardiac arrest in 2012, and is the senior author of the revised guidelines in 2016. He coauthored the European Resuscitation Council (ERC) 2015 guidelines on postarrest care. I had the distinct pleasure of hosting Dr. Cronberg at Yale in 2016, when he presented his research at one of our named lectureships for the Department of Neurology. His contributions to the field are insightful, innovative, and impactful.

Dr. Friberg is Professor of Anesthesia and Intensive Care Medicine at Lund University. Dr. Friberg did his PhD work at the Laboratory for Experimental Brain Research at Lund University, where he studied brain ischemia in different rodent models. He is presently involved in several trials in the field of cardiac arrest and has published more than 100 peer-reviewed papers in resuscitation science. He was the senior author of the TTM Trial and shares the senior investigator role for the TTM-2 Trial. Another focus of his interests is the assessment of brain injury in comatose survivors after cardiac arrest using a multimodal strategy, including continuous electroencephalography, somatosensory evoked potentials, biomarkers, and neuroimaging in addition to clinical investigation. He was the senior author of the national Swedish recommendations on neurologic prognostication after cardiac arrest in 2012 and a coauthor of the revised guidelines in 2016. He is also a coauthor of the recently published joint advisory statement on prognostication after cardiac arrest from the ERC and the European Society of Intensive Care Medicine. He presently holds the Chair of the Post-Resuscitation Care Committee of the Swedish Resuscitation Council. Dr. Friberg was one of the initiators of the Hypothermia Network, which has now become the International Cardiac Arrest Registry (INTCAR), a trans-Atlantic research collaboration with more than 5,000 registered cardiac arrest patients in Europe and the United States. He is one of the pioneers and leaders in the field of postcardiac arrest care and prognostication.

We greatly appreciate the efforts of Drs. Cronberg and Friberg, as well as all of the contributing authors, for their great work in this issue of Seminars. The issue provides a comprehensive review of hypoxic–ischemic brain injury following cardiac arrest, and brings together a diverse group of authors and topics that provide the reader with a thorough review of the topic. I am personally indebted to Drs. Cronberg and Friberg for their contributions to this all-important area, and for their continued friendship. We hope that you enjoy this truly superb issue!