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Thromb Haemost 1998; 80(02): 342-343
DOI: 10.1055/s-0037-1615199
Letters to the Editor
Schattauer GmbH

Prevalence of the Factor II G20210A Mutation in Symptomatic Patients with Inherited Thrombophilia

Valerio De Stefano
1   Department of Hematology, Catholic University, Rome, Italy
,
Patrizia Chiusolo
1   Department of Hematology, Catholic University, Rome, Italy
,
Katia Paciaroni
1   Department of Hematology, Catholic University, Rome, Italy
,
Ida Casorelli
1   Department of Hematology, Catholic University, Rome, Italy
,
Antonella Di Mario
1   Department of Hematology, Catholic University, Rome, Italy
,
Elena Rossi
1   Department of Hematology, Catholic University, Rome, Italy
,
Giuseppe Leone
1   Department of Hematology, Catholic University, Rome, Italy
› Author Affiliations
Further Information

Publication History

Received 26 January 1998

Accepted after revision 07 April 1998

Publication Date:
08 December 2017 (online)

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  • References

  • 1 Poort SR, Rosendaal FR, Reitsma PH, Bertina RM. A common genetic variation in the 3’-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood 1996; 88: 3698-703.
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  • 2 Makris M, Preston FE, Beauchamp NJ, Cooper PC, Daly ME, Hampton KK, Bayliss P, Peake IR, Miller GJ. Co-inheritance of the 20210A allele of the prothrombin gene increases the risk of thrombosis in subjects with a familial thrombophilia. Thromb Haemost 1997; 78: 1426-9.
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  • 3 Alhenc-Gelas M, Le Cam-Duchez V, Emmerich J, Frebourg T, Fiessinger J-N, Borg J-Y, Aiach M. The A20210 allele of the prothrombin gene is not frequently associated with the Factor V Arg 506 to Gln mutation in thrombophilic families. Blood 1997; 90: 1711.
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