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Digestive Disease Interventions 2018; 02(03): 231-239
DOI: 10.1055/s-0038-1668568
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Middle Aortic Syndrome: Pathogenesis, Visceral Manifestations, and Management

Eric J. Monroe
1   Department of Radiology, Seattle Children's Hospital, Seattle, Washington
2   Department of Radiology, University of Washington, Seattle, Washington
,
Brian H. Morray
3   Division of Pediatric Cardiology, Seattle Children's Hospital, Seattle, Washington
,
Yongdong Zhao
4   Department of Pediatrics, Seattle Children's Hospital, Seattle, Washington
5   Department of Pediatrics, University of Washington, Seattle, Washington
,
Caitlin A. Smith
6   Department of Surgery, Seattle Children's Hospital, Seattle, Washington
› Author Affiliations
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Publication History

02 July 2018

09 July 2018

Publication Date:
20 August 2018 (online)

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Abstract

Middle aortic syndrome (MAS) is characterized by severe narrowing of the abdominal aorta, frequently involving the great abdominal vessels. Although increasingly implicated in primary hypertension, up to one-third of cases affect the mesenteric vasculature, and the resultant manifestations may be underrecognized. Early intervention with interdisciplinary medical management and invasive arterial reconstruction affords preservation of end-organ function and improvement in patient survival. This article reviews the embryology of the thoracoabdominal aorta and major abdominal arteries, as well as the pathogenesis, clinical manifestations, and management of the nonatherosclerotic abdominal coarctation otherwise known as MAS.

Keywords

middle aortic syndrome - visceral manifestations - pathogenesis
 

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