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Semin Respir Crit Care Med 2018; 39(06): 649-660
DOI: 10.1055/s-0038-1676646
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Linear Endobronchial Ultrasound: What's New?

Tao He
1   Division of Pulmonary, Critical Care Medicine, Allergy, and Clinical Immunology, David Geffen School of Medicine at UCLA, Los Angeles, California
,
Atul C. Mehta
2   Department of Pulmonary Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, Ohio
› Author Affiliations
Further Information

Publication History

Publication Date:
14 January 2019 (online)

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Abstract

Since its advent more than a decade ago, real-time linear endobronchial ultrasound (EBUS) guided transbronchial needle aspiration has revolutionized the diagnosis and staging of nonsmall cell lung cancer (NSCLC), and has become the standard of care with widespread acceptance. It is also extensively used to diagnose other disease entities such as malignancy besides NSCLC, benign diseases, or infectious processes. Ancillary studies have shown its superior safety profile and cost-effectiveness. In recent years, linear EBUS has been expanding its clinical applications owing to the emerging new tools such as the 19-gauge (19G) needle and miniforceps. Meanwhile, with several ground-breaking discoveries in lung cancer treatment over the past few years, linear EBUS has found its way to fit into this scheme as a safe and effective diagnostic tool. This review summarizes the most recent evidence on evaluating the performance of linear EBUS-guided biopsy in various clinical situations.

Keywords

linear endobronchial ultrasound - needle aspiration - 19G needle - miniforceps - targeted therapy - immunotherapy - rebiopsy - next generation sequencing
 

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