Semin Musculoskelet Radiol 2019; 23(05): 523-533
DOI: 10.1055/s-0039-1695719
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Osteonecrosis of the Upper Extremity: MRI-Based Zonal Patterns and Differential Diagnosis

1   Department of Radiology, Rhön-Klinikum AG, Bad Neustadt, Germany
2   Department of Radiology, University Hospital Würzburg, Würzburg, Germany
,
K.H. Kalb
3   Department of Hand Surgery, Rhön-Klinikum AG, Bad Neustadt, Germany
,
G. Christopoulos
1   Department of Radiology, Rhön-Klinikum AG, Bad Neustadt, Germany
,
J.P. Grunz
1   Department of Radiology, Rhön-Klinikum AG, Bad Neustadt, Germany
2   Department of Radiology, University Hospital Würzburg, Würzburg, Germany
› Author Affiliations
Further Information

Publication History

Publication Date:
25 September 2019 (online)

Abstract

Regarding the upper extremity, osteonecrosis can relate to the humeral head and to any carpal bone, most commonly the lunate (Kienböck's disease), scaphoid (Preiser's disease and nonunion), and capitate bone (osteonecrosis of the capitate head). In children and adolescents, osteochondrosis is an important differential diagnosis at the epiphyses. Appropriate imaging of osteonecrosis depends on knowledge about blood supply, biomechanical load, and bone repair mechanisms. Contrast-enhanced MRI (ceMRI) enables the differentiation of up to three mostly band-shaped zones: necrotic tissue (proximal), hypervascular repair tissue (intermediate), and viable bone (distal). To distinguish between necrotic and repair zones, intravenous gadolinium is recommended in MRI. Osteosclerosis and insufficiency fractures in early and intermediate stages as well as osteoarthritis in advanced stages are best depicted using high-resolution CT (HRCT). The combination of HRCT and ceMRI allows for exact classification of osteonecrosis regarding morphology and viability.

 
  • References

  • 1 Gelberman RH, Bauman TD, Menon J, Akeson WH. The vascularity of the lunate bone and Kienböck's disease. J Hand Surg Am 1980; 5 (03) 272-278
  • 2 Lluch A, Garcia-Elias M. Etiology of Kienböck disease. Tech Hand Up Extrem Surg 2011; 15 (01) 33-37
  • 3 Gelberman RH, Menon J. The vascularity of the scaphoid bone. J Hand Surg Am 1980; 5 (05) 508-513
  • 4 Ståhl F. On lunatomalacia (Kienboeck's disease): a clinical und roentgenological study, especially on its pathogenesis and the late results of immobilization treatment. Acta Chir Scand 1947; 126 (01) 1-133
  • 5 White Jr RE, Omer Jr GE. Transient vascular compromise of the lunate after fracture-dislocation or dislocation of the carpus. J Hand Surg Am 1984; 9 (02) 181-184
  • 6 Schiltenwolf M, Martini AK, Mau HC, Eversheim S, Brocai DRC, Jensen CH. Further investigations of the intraosseous pressure characteristics in necrotic lunates (Kienböck's disease). J Hand Surg Am 1996; 21 (05) 754-758
  • 7 Hultén O. Über die Entstehung und Behandlung der Lunatumnekrose. Acta Chir Scand 1935; 76: 121-135
  • 8 Gelberman RH, Salamon PB, Jurist JM, Posch JL. Ulnar variance in Kienböck's disease. J Bone Joint Surg Am 1975; 57 (05) 674-676
  • 9 van Leeuwen WF, Tarabochia MA, Schuurman AH, Chen N, Ring D. Risk factors of lunate collapse in Kienböck disease. J Hand Surg Am 2017; 42 (11) 883-888.e1
  • 10 Desser TS, McCarthy S, Trumble T. Scaphoid fractures and Kienbock's disease of the lunate: MR imaging with histopathologic correlation. Magn Reson Imaging 1990; 8 (04) 357-361
  • 11 Trumble TE, Irving J. Histologic and magnetic resonance imaging correlations in Kienböck's disease. J Hand Surg Am 1990; 15 (06) 879-884
  • 12 Aspenberg P, Wang JS, Jonsson K, Hagert CG. Experimental osteonecrosis of the lunate. Revascularization may cause collapse. J Hand Surg [Br] 1994; 19 (05) 565-569
  • 13 Hashizume H, Asahara H, Nishida K, Inoue H, Konishiike T. Histopathology of Kienböck's disease. Correlation with magnetic resonance and other imaging techniques. J Hand Surg [Br] 1996; 21 (01) 89-93
  • 14 Ogawa T, Nishiura Y, Hara Y, Okamoto Y, Ochiai N. Correlation of histopathology with magnetic resonance imaging in Kienböck disease. J Hand Surg Am 2012; 37 (01) 83-89
  • 15 Kalb K, Pillukat T, Schmitt R, Prommersberger KJ. Kienböck's disease in paediatric and juvenile patients [in German]. Handchir Mikrochir Plast Chir 2010; 42 (03) 187-197
  • 16 Hidaka Y, Nakamura R. Progressive patterns of degenerative arthritis in scaphoid nonunion demonstrated by three-dimensional computed tomography. J Hand Surg [Br] 1998; 23 (06) 765-770
  • 17 Coblenz G, Christopoulos G, Fröhner S, Kalb KH, Schmitt R. Scaphoid fracture and nonunion: current status of radiological diagnostics [in German]. Radiologe 2006; 46 (08) 664 , 666–676
  • 18 Schmitt R, Heinze A, Fellner F, Obletter N, Strühn R, Bautz W. Imaging and staging of avascular osteonecroses at the wrist and hand. Eur J Radiol 1997; 25 (02) 92-103
  • 19 Schmitt R, Kalb K. Imaging in Kienböck's disease [in German]. Handchir Mikrochir Plast Chir 2010; 42 (03) 162-170
  • 20 Schmitt R, Christopoulos G, Wagner M. , et al. Avascular necrosis (AVN) of the proximal fragment in scaphoid nonunion: is intravenous contrast agent necessary in MRI?. Eur J Radiol 2011; 77 (02) 222-227
  • 21 Decoulx P, Marchand M, Minet P, Razemon JP. La maladie de Kienbock chez le mineur; étude clinique et pathogénique avec analyse de 1330 radios de poignet. Lille Chir 1957; 12 (02) 65-81
  • 22 Nattrass GR, King GJ, McMurtry RY. , et al. An alternative method for determination of the carpal height ratio. J Bone Joint Surg Am 1994; 76: 88-94
  • 23 Youm Y, McMurthy RY, Flatt AE, Gillespie TE. Kinematics of the wrist. I. An experimental study of radial-ulnar deviation and flexion-extension. J Bone Joint Surg Am 1978; 60 (04) 423-431
  • 24 Friedman L, Yong-Hing K, Johnston GH. The use of coronal computed tomography in the evaluation of Kienbock's disease. Clin Radiol 1991; 44 (01) 56-59
  • 25 Vande Berg BC, Malghem J, Lecouvet FE, Maldague B. MRI of the normal bone marrow. Skeletal Radiol 1998; 27 (09) 471-483
  • 26 Sowa DT, Holder LE, Patt PG, Weiland AJ. Application of magnetic resonance imaging to ischemic necrosis of the lunate. J Hand Surg Am 1989; 14 (06) 1008-1016
  • 27 Reinus WR, Conway WF, Totty WG. , et al. Carpal avascular necrosis: MR imaging. Radiology 1986; 160 (03) 689-693
  • 28 Cerezal L, Abascal F, Canga A, García-Valtuille R, Bustamante M, del Piñal F. Usefulness of gadolinium-enhanced MR imaging in the evaluation of the vascularity of scaphoid nonunions. AJR Am J Roentgenol 2000; 174 (01) 141-149
  • 29 Donati OF, Zanetti M, Nagy L, Bode B, Schweizer A, Pfirrmann CW. Is dynamic gadolinium enhancement needed in MR imaging for the preoperative assessment of scaphoidal viability in patients with scaphoid nonunion?. Radiology 2011; 260 (03) 808-816
  • 30 Lichtman DM, Ross G. Revascularization of the lunate in Kienböck's disease. In: Gelberman RH. , ed. The Wrist. New York, NY: Raven Press; 1994: 363-372
  • 31 Goldfarb CA, Hsu J, Gelberman RH, Boyer MI. The Lichtman classification for Kienböck's disease: an assessment of reliability. J Hand Surg Am 2003; 28 (01) 74-80
  • 32 Schmitt R, Christopoulos G, Kalb K. , et al. Differential diagnosis of the signal-compromised lunate in MRI [in German]. RoFo Fortschr Geb Rontgenstr Nuklearmed 2005; 177 (03) 358-366
  • 33 Arnaiz J, Piedra T, Cerezal L. , et al. Imaging of Kienböck disease. AJR Am J Roentgenol 2014; 203 (01) 131-139
  • 34 Cerezal L, del Piñal F, Abascal F, García-Valtuille R, Pereda T, Canga A. Imaging findings in ulnar-sided wrist impaction syndromes. Radiographics 2002; 22 (01) 105-121
  • 35 Imaeda T, Nakamura R, Shionoya K, Makino N. Ulnar impaction syndrome: MR imaging findings. Radiology 1996; 201 (02) 495-500
  • 36 Steinborn M, Schürmann M, Staebler A. , et al. MR imaging of ulnocarpal impaction after fracture of the distal radius. AJR Am J Roentgenol 2003; 181 (01) 195-198
  • 37 Trojan E, Jahna H. Conservative treatment of old scaphoid fractures of the hand [in German]. Arch Orthop Unfallchir 1955; 47 (01) 99-104
  • 38 Vender MI, Watson HK, Wiener BD, Black DM. Degenerative change in symptomatic scaphoid nonunion. J Hand Surg Am 1987; 12 (04) 514-519
  • 39 Crema MD, Zentner J, Guermazi A, Jomaah N, Marra MD, Roemer FW. Scapholunate advanced collapse and scaphoid nonunion advanced collapse: MDCT arthrography features. AJR Am J Roentgenol 2012; 199 (02) W202-7
  • 40 Vogl TJ, Beutel F, Wilhelm K. , et al. The MRT of scaphoid pseudarthrosis with Gd-DTPA. Its staging and clinical correlation [in German]. RoFo Fortschr Geb Rontgenstr Nuklearmed 1994; 161 (05) 438-445
  • 41 Lauder AJ, Trumble TE. Idiopathic avascular necrosis of the scaphoid: Preiser's disease. Hand Clin 2006; 22 (04) 475-484 ; abstract vi
  • 42 Kalainov DM, Cohen MS, Hendrix RW, Sweet S, Culp RW, Osterman AL. Preiser's disease: identification of two patterns. J Hand Surg Am 2003; 28 (05) 767-778
  • 43 Schmitt R, Fröhner S, van Schoonhoven J, Lanz U, Gölles A. Idiopathic osteonecrosis of the scaphoid (Preiser's disease)—MRI gives new insights into etiology and pathology. Eur J Radiol 2011; 77 (02) 228-234
  • 44 Prommersberger KJ, van Schoonhoven J, Lanz U. Aseptic necrosis of the capitate: a rare cause for wrist pain. Case report and review of the literature [in German]. Handchir Mikrochir Plast Chir 2000; 32 (02) 123-128
  • 45 Peters SJ, Degreef I, De Smet L. Avascular necrosis of the capitate: report of six cases and review of the literature. J Hand Surg Eur Vol 2015; 40 (05) 520-525
  • 46 Fenton RL. The naviculo-capitate fracture syndrome. J Bone Joint Surg Am 1956; 38-A (03) 681-684
  • 47 Gerber C, Schneeberger AG, Vinh TS. The arterial vascularization of the humeral head. An anatomical study. J Bone Joint Surg Am 1990; 72 (10) 1486-1494
  • 48 Lee JA, Farooki S, Ashman CJ, Yu JS. MR patterns of involvement of humeral head osteonecrosis. J Comput Assist Tomogr 2002; 26 (05) 839-842
  • 49 Sakai T, Sugano N, Nishii T, Hananouchi T, Yoshikawa H. Extent of osteonecrosis on MRI predicts humeral head collapse. Clin Orthop Relat Res 2008; 466 (05) 1074-1080
  • 50 Vande Berg BC, Malghem J, Lecouvet FE, Noel H, Maldague B. MR imaging of bone infarction and epiphyseal osteonecrosis. J Belge Radiol 1997; 80 (05) 243-250
  • 51 Munk PL, Helms CA, Holt RG. Immature bone infarcts: findings on plain radiographs and MR scans. AJR Am J Roentgenol 1989; 152 (03) 547-549
  • 52 Doyle SM, Monahan A. Osteochondroses: a clinical review for the pediatrician. Curr Opin Pediatr 2010; 22 (01) 41-46
  • 53 Danger F, Wasyliw C, Varich L. Osteochondroses. Semin Musculoskelet Radiol 2018; 22 (01) 118-124
  • 54 Lichtman DM, Pientka II WF, Bain GI. Kienböck disease: a new algorithm for the 21st century. J Wrist Surg 2017; 6 (01) 2-10
  • 55 Stahl S, Hentschel P, Ketelsen D. , et al. Results of a prospective clinical study on the diagnostic performance of standard magnetic resonance imaging in comparison to a combination of 3T MRI and additional CT imaging in Kienböck's disease. Eur J Radiol 2017; 90 (05) 212-219