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Methods Inf Med 2019; 58(06): 229-234
DOI: 10.1055/s-0040-1709158
FAIR principles in Health Research
Georg Thieme Verlag KG Stuttgart · New York

Applying FAIRness: Redesigning a Biomedical Informatics Research Data Management Pipeline

Marcel Parciak
1   Department of Medical Informatics, University Medical Center Göttingen, Göttingen, Niedersachsen, Germany
,
Theresa Bender
1   Department of Medical Informatics, University Medical Center Göttingen, Göttingen, Niedersachsen, Germany
,
Ulrich Sax
1   Department of Medical Informatics, University Medical Center Göttingen, Göttingen, Niedersachsen, Germany
,
Christian Robert Bauer
1   Department of Medical Informatics, University Medical Center Göttingen, Göttingen, Niedersachsen, Germany
› Author Affiliations Funding This work was supported by the German Federal Ministry of Education and Research (BMBF) within the framework of the research and funding concepts of the Medical Informatics Initiative (01ZZ1802B/HiGHmed) and MyPathSem (BMBF 031L0024A).
Further Information

Publication History

30 July 2019

22 February 2020

Publication Date:
29 April 2020 (online)

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Abstract

Background Managing research data in biomedical informatics research requires solid data governance rules to guarantee sustainable operation, as it generally involves several professions and multiple sites. As every discipline involved in biomedical research applies its own set of tools and methods, research data as well as applied methods tend to branch out into numerous intermediate and output data objects, making it very difficult to reproduce research results.

Objectives This article gives an overview of our implementation status applying the Findability, Accessibility, Interoperability and Reusability (FAIR) Guiding Principles for scientific data management and stewardship onto our research data management pipeline focusing on the software tools that are in use.

Methods We analyzed our progress FAIRificating the whole data management pipeline, from processing non-FAIR data up to data usage. We looked at software tools for data integration, data storage, and data usage as well as how the FAIR Guiding Principles helped to choose appropriate tools for each task.

Results We were able to advance the degree of FAIRness of our data integration as well as data storage solutions, but lack enabling more FAIR Guiding Principles regarding Data Usage. Existing evaluation methods regarding the FAIR Guiding Principles (FAIRmetrics) were not applicable to our analysis of software tools.

Conclusion Using the FAIR Guiding Principles, we FAIRificated relevant parts of our research data management pipeline improving findability, accessibility, interoperability and reuse of datasets and research results. We aim to implement the FAIRmetrics to our data management infrastructure and—where required—to contribute to the FAIRmetrics for research data in the biomedical informatics domain as well as for software tools to achieve a higher degree of FAIRness of our research data management pipeline.

Keywords

data quality - data management - data analysis - data linkage
 

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