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Journal of Pediatric Neurology 2021; 19(01): 054-058
DOI: 10.1055/s-0040-1710515
Case Report

Neurological Nuance: Sporadic Burkitt's Lymphoma Presenting with Guillain–Barre Syndrome

Nadia Bouattour
1   Department of Child Neurology, Hedi Chaker Hospital, Sfax, Tunisia
,
Fatma Kamoun
1   Department of Child Neurology, Hedi Chaker Hospital, Sfax, Tunisia
2   Research Laboratory “Neuropediatrics,” University of Sfax, Sfax, Tunisia
,
Slim Charfi
3   Department of Pathology, Habib Bourguiba Hospital, Sfax, Tunisia
,
Siham Ben Nsir
1   Department of Child Neurology, Hedi Chaker Hospital, Sfax, Tunisia
2   Research Laboratory “Neuropediatrics,” University of Sfax, Sfax, Tunisia
,
Wafa Bouchaala
1   Department of Child Neurology, Hedi Chaker Hospital, Sfax, Tunisia
2   Research Laboratory “Neuropediatrics,” University of Sfax, Sfax, Tunisia
,
Tahya Boudawara
3   Department of Pathology, Habib Bourguiba Hospital, Sfax, Tunisia
,
Chahnez Triki
1   Department of Child Neurology, Hedi Chaker Hospital, Sfax, Tunisia
2   Research Laboratory “Neuropediatrics,” University of Sfax, Sfax, Tunisia
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Abstract

Burkitt's lymphoma (BL) is a high-grade mature B cell neoplasm. Primary lymphoma of the central nervous system (CNS) is very rare. In contrast, BL can be localized in any part of the body and may spread to the CNS. Peripheral nervous system impairment caused by BL has been thoroughly described. However, Guillain–Barre syndrome (GBS) does not commonly appear as an initial manifestation of BL. We presented the case of a young child with sporadic BL with neuromeningeal involvement and spinal cord compression whose first clinical manifestation was the appearance of GBS. Lymphoma should be taken into account, especially in children presenting with the clinical features of acute polyradiculoneuropathy.

Keywords

Guillain–Barre's syndrome - Burkitt's lymphoma - lymphoma - neurology


Publication History

Received: 01 February 2020

Accepted: 07 April 2020

Article published online:
12 May 2020

© 2020. Thieme. All rights reserved.

Georg Thieme Verlag KG
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