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Journal of Pediatric Neurology 2021; 19(04): 282-285
DOI: 10.1055/s-0040-1716868
Case Report

Multiple Ischemic Strokes Associated with Childhood Progressive Radiation-Induced Occlusive Cerebral Vasculopathy

Daniela Garcez
1   Department of Neurology, Instituto Português de Oncologia de Lisboa, Lisboa, Portugal
,
João Passos
1   Department of Neurology, Instituto Português de Oncologia de Lisboa, Lisboa, Portugal
,
Cátia Pedro
2   Department of Radiation Oncology, Instituto Português de Oncologia de Lisboa, Lisboa, Portugal
,
Hipólito Nzwalo 
3   Department of Biomedical Sciences and Medicine, Universidade do Algarve, Faro, Portugal
,
Sofia Nunes
4   Department of Pediatric Oncology, Instituto Português de Oncologia de Lisboa, Lisboa, Portugal
,
Alexandra Borges
5   Department of Radiology, Instituto Português de Oncologia de Lisboa, Lisboa, Portugal
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Abstract

There is little knowledge on the pathophysiology of pediatric stroke associated with radiation-induced occlusive cerebral vasculopathy (RIOCV). Herein, we present an extremely rare case of a child with multiple ischemic strokes in association with progressive RIOCV. The possibility of hemodynamic compromise and artery-to-artery embolism as a cause of the ischemic events is discussed.

Keywords

pediatric - stroke - radiation-induced - occlusive cerebral vasculopathy


Publication History

Received: 08 June 2020

Accepted: 17 August 2020

Article published online:
21 September 2020

© 2020. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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