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Dtsch Med Wochenschr 2015; 140(16): 1223-1226
DOI: 10.1055/s-0041-103783
Klinischer Fortschritt
Rheumatologie
© Georg Thieme Verlag KG Stuttgart · New York

Gelenk-Ultraschall bei rheumatoider Arthritis

Ultrasound examination in rheumatoid arthritis
Sarah Ohrndorf
1   Abteilung für Rheumatologie und klinische Immunologie, Charité Universitätsmedizin Berlin
,
Marina Backhaus
1   Abteilung für Rheumatologie und klinische Immunologie, Charité Universitätsmedizin Berlin
2   Abteilung Innere Medizin- Rheumatologie und Klinische Immunologie, Akademisches Lehrkrankenhaus der Charité, Park-Klinik Weissensee, Berlin
› Author Affiliations
Further Information

Publication History

Publication Date:
11 August 2015 (online)

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Zusammenfassung

Der Ultraschall am Bewegungsapparat in der rheumatologischen Routinediagnostik erhöht die diagnostische Trefferquote in der Ermittlung einer entzündlichen Gelenkerkrankung.

Der Power-Doppler-Ultraschall ist hilfreich, um eine subklinische Synovitis der kleinen Fingergelenke bei Patienten mit einer rheumatoiden Arthritis nachzuweisen, die zum Progress der Knochendestruktion führen kann. Strenge klinische Remissionskriterien gehen mit einer geringeren Synovitis im Power Doppler einher.

Abstract

Musculoskeletal ultrasound in the clinical routine praxis increases the hit rate for the diagnosis of inflammatory joint diseases.

Power Doppler ultrasound is helpful in the detection of subclinical synovitis in the small finger joints in patients with rheumatoid arthritis; subclinical synovitis can lead to severe joint destruction. Rigorous clinical remission criteria result in lower synovitis detected by power Doppler ultrasound.

Schlüsselwörter

Arthrosonografie - rheumatoide Arthritis - Synovitis

Keywords

musculoskeletal ultrasound - rheumatoid arthritis - synovitis
 

  • Literatur

  • 1 Nakagomi D, Ikeda K, Okubo A et al. Ultrasound can improve the accuracy of the 2010 American College of Rheumatology / European League against rheumatism classification criteria for rheumatoid arthritis to predict the requirement for methotrexate treatment. Arthritis Rheum 2013; 65: 890-898
    CrossrefPubMedGoogle Scholar
  • 2 Xiao H, Liu M, Tan L et al. Value of ultrasonography for diagnosis of synovitis associated with rheumatoid arthritis. Int J Rheum Dis 2014; 17: 767-775
    CrossrefPubMedGoogle Scholar
  • 3 Rezaei H, Torp-Pedersen S, af Klint E et al. Diagnostic utility of musculoskeletal ultrasound in patients with suspected arthritis – a probabilistic approach. Arthritis Res Ther 2014; 16: 448
    CrossrefPubMedGoogle Scholar
  • 4 Janta I, Naredo E, Martínez-Estupiñán L et al. Patient self-assessment and physician’s assessment of rheumatoid arthritis activity: which is more realistic in remission status? A comparison with ultrasonography. Rheumatology (Oxford) 2013; 52: 2243-2250
    CrossrefPubMedGoogle Scholar
  • 5 Cheung PP, Gossec L, Ruyssen-Witrand A et al. The relationship of patient-reported joints with active synovitis detected by power Doppler ultrasonography in rheumatoid arthritis. Clin Exp Rheumatol 2013; 31: 490-497
    PubMedGoogle Scholar
  • 6 Pedersen jK, Lorenzen T, Ejbjerg B et al. Low-field magnetic resonance imaging or combined ultrasonography and anti-cyclic citrullinated peptide antibody improve correct classification of individuals as established rheumatoid arthritis: results of a population-based, cross-sectional study. BMC Musculoskelet Disord 2014; 15: 268
    CrossrefPubMedGoogle Scholar
  • 7 Sant’Ana Petterle G, Natour J, Rodrigues da Luz K et al. Usefulness of US to show subclinical joint abnormalities in asymptomatic feet of RA-Patients compared to healthy controls. Clin Exp Rheumatol 2013; 31: 904-912
    PubMedGoogle Scholar
  • 8 Tian J, Chen J, Li F et al. [Grey scale and power Doppler ultrasonographic assessment of bone erosion and disease activity in early rheumatoid arthritis]. Zhong Nan Da Xue Xue Bao Yi Xue Ban 2013; 38: 1270-1274
    PubMedGoogle Scholar
  • 9 Ogishima H, Tsuboi H, Umeda N et al. Analysis of subclinical synovitis detected by ultrasonography and low-field magnetic resonance imaging in patients with rheumatoid arthritis. Mod Rheumatol 2014; 24: 60-68
    PubMedGoogle Scholar
  • 10 Ikeda K, Nakagomi D, Sanayama Y et al. Correlation of radiographic progression with the cumulative activity of synovitis estimated by power Doppler ultrasound in rheumatoid arthritis: difference between patients treated with methotrexate and those treated with biological agents. J Rheumatol 2013; 40: 1967-1976
    CrossrefPubMedGoogle Scholar
  • 11 Kawashiri SY, Suzuki T, Nakashima Y et al. Ultrasonographic examination of rheumatoid arthritis patients who are free of physical synovitis: power Doppler subclinical synovitis is associated with bone erosion. Rheumatology (Oxford) 2014; 53: 562-569
    CrossrefPubMedGoogle Scholar
  • 12 Guillén Astete CA, Boteanu A, Zea Mendoza A. Comparison of Prevalence of Synovitis by Ultrasound Assessment in Subjects Exposed or Not to Self-Reported Physical Overexertion: The Monday’s Synovitis. ScientificWorldJournal 2014; 2014: 563 981
    PubMedGoogle Scholar
  • 13 Min-Kyu K, Hong-Jun J, Se-Hyuck P et al. Value of Ultrasonography in the Diagnosis of Carpal Tunnel Syndrome: Correlation with Electrophysiological Abnormalities and Clinical Severity. J Korean Neurosurg So 2014; 55: 78-82
    PubMedGoogle Scholar
  • 14 Kwon HK, Kang HJ, Byun CW et al. Correlation between Ultrasonography Findings and Electrodiagnostic Severity in Carpal Tunnel Syndrome: 3D Ultrasonography. J Clin Neurol 2014; 10: 348-353
    CrossrefPubMedGoogle Scholar
  • 15 Tokai N, Ogasawara M, Gorai M et al. Predictive value of bone destruction and duration of clinical remission for subclinical synovitis in rheumatoid arthritis patients. Mod Rheumatol 2015; 25: 540-545
    CrossrefPubMedGoogle Scholar
  • 16 Zufferey P, Möller B, Brulhart L et al. Persistence of ultrasound synovitis in patients with rheumatoid arthritis fulfilling the DAS28 and / or the new ACR / EULAR RA remission definitions: Results of an observational cohort study. Joint Bone Spine 2014; 81: 426-432
    CrossrefPubMedGoogle Scholar
  • 17 Geng Y, Han J, Deng X, Zhang Z. Presence of power Doppler synovitis in rheumatoid arthritis patients with synthetic and / or biological disease-modifying anti-rheumatic drug-induced clinical remission: experience from a Chinese cohort. Clin Rheumatol 2014; 33: 1061-1066
    CrossrefPubMedGoogle Scholar
  • 18 Nguyen H, Ruyssen-Witrand A, Gandjbakhch F et al. Prevalence of ultrasound-detected residual synovitis and risk of relapse and structural progression in rheumatoid arthritis patients in clinical remission: a systematic review and meta-analysis. Rheumatology (Oxford) 2014; 53: 2110-2118
    CrossrefPubMedGoogle Scholar
  • 19 Ramírez J, Ruíz-Esquide V, Pomés I et al. Patients with rheumatoid arthritis in clinical remission and ultrasound-defined active synovitis exhibit higher disease activity and increased serum levels of angiogenic biomarkers. Arthritis Res Ther 2014; 16: R5
    CrossrefPubMedGoogle Scholar
  • 20 Dale J, Purves D, McConnachie A et al. Tightening up? Impact of musculoskeletal ultrasound disease activity assessment on early rheumatoid arthritis patients treated using a treat to target strategy. Arthritis Care Res (Hoboken) 2014; 66: 19-26
    CrossrefPubMedGoogle Scholar
  • 21 Ceponis A, Onishi M, Bluestein HG et al. Utility of the ultrasound examination of the hand and wrist joints in the management of established rheumatoid arthritis. Arthritis Care Res (Hoboken) 2014; 66: 236-244
    CrossrefPubMedGoogle Scholar
  • 22 Reiche BE, Ohrndorf S, Feist E et al. Usefulness of power Doppler ultrasound for prediction of re-therapy with rituximab in rheumatoid arthritis: a prospective study of longstanding rheumatoid arthritis patients. Arthritis Care Res (Hoboken) 2014; 66: 204-216
    CrossrefPubMedGoogle Scholar
  • 23 Zufferey P, Brulhart L, Tamborrini G et al. Ultrasound evaluation of synovitis in RA: Correlation with clinical disease activity and sensitivity to change in an observational cohort study. Joint Bone Spine 2014; 81: 222-227
    CrossrefPubMedGoogle Scholar
  • 24 Witt M, Mueller F, Nigg A et al. Relevance of grade 1 gray-scale ultrasound findings in wrists and small joints to the assessment of subclinical synovitis in rheumatoid arthritis. Arthritis Rheum 2013; 65: 1694-1701
    CrossrefPubMedGoogle Scholar