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Semin Neurol 2021; 41(02): 206-216
DOI: 10.1055/s-0041-1725137
Review Article

Brain–Computer Interfaces in Neurorecovery and Neurorehabilitation

Michael J. Young
1   Department of Neurology, Center for Neurotechnology and Neurorecovery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
,
David J. Lin
1   Department of Neurology, Center for Neurotechnology and Neurorecovery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
2   School of Engineering and Carney Institute for Brain Science, Brown University, Providence, Rhode Island
3   Department of Veterans Affairs Medical Center, VA RR&D Center for Neurorestoration and Neurotechnology, Providence, Rhode Island
,
Leigh R. Hochberg
1   Department of Neurology, Center for Neurotechnology and Neurorecovery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
2   School of Engineering and Carney Institute for Brain Science, Brown University, Providence, Rhode Island
3   Department of Veterans Affairs Medical Center, VA RR&D Center for Neurorestoration and Neurotechnology, Providence, Rhode Island
› Author Affiliations Funding This work was supported by the NIH BRAIN Initiative, National Institute of Mental Health, F32MH123001, National Institute of Neurologic Diseases and Stroke, UH2NS095548; National Institute on Deafness and Other Communication Disorders, U01DC017844; Henry and Allison McCance Center for Brain Health/Mass General Neuroscience SPARC Award; Office of Research and Development, Rehabilitation R&D Service, U.S. Department of Veterans Affairs (N2864C, A2295R). The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH or the Department of Veterans Affairs or the U.S. government. The funders had no role in the design, analysis, preparation, review, approval or decision to submit this manuscript for publication.
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Abstract

Recent advances in brain–computer interface technology to restore and rehabilitate neurologic function aim to enable persons with disabling neurologic conditions to communicate, interact with the environment, and achieve other key activities of daily living and personal goals. Here we evaluate the principles, benefits, challenges, and future directions of brain–computer interfaces in the context of neurorehabilitation. We then explore the clinical translation of these technologies and propose an approach to facilitate implementation of brain–computer interfaces for persons with neurologic disease.

Keywords

brain–computer interface - neurorecovery - neurorehabilitation - neurotechnology - brain–machine interface

Disclosure

The MGH Translational Research Center has a clinical research support agreement with Neuralink, Paradromics, and Synchron, for which L.R.H. provides consultative input.




Publication History

Article published online:
19 March 2021

© 2021. Thieme. All rights reserved.

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