J Reconstr Microsurg 2022; 38(03): 221-227
DOI: 10.1055/s-0041-1740955
Review Article

Current Applications of Ultrasound Imaging in the Preoperative Planning of DIEP Flaps

Carolina Torres Perez-Iglesias
1   Division of Plastic and Reconstructive Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts
,
Elizabeth Laikhter
1   Division of Plastic and Reconstructive Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts
,
1   Division of Plastic and Reconstructive Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts
,
1   Division of Plastic and Reconstructive Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts
,
Amy M. Maselli
1   Division of Plastic and Reconstructive Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts
,
Ryan Cauley
1   Division of Plastic and Reconstructive Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts
,
Bernard T. Lee
1   Division of Plastic and Reconstructive Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts
› Author Affiliations

Abstract

Background The deep inferior epigastric artery perforator (DIEP) flap has become the gold standard for autologous breast reconstruction at many institutions. Although the deep inferior epigastric artery displays significant anatomic variability in its intramuscular course, branching pattern and location of perforating vessels, the ability to preoperatively visualize and map relevant vascular anatomy has increased the efficiency, safety and reliability of the DIEP flap. While computed tomography angiography (CTA) is often cited as the preoperative imaging modality of choice for perforator flaps, more recent advances in ultrasound technology have made it an increasingly attractive alternative.

Methods An extensive literature review was performed to identify the most common applications of ultrasound technology in the preoperative planning of DIEP flaps.

Results This review demonstrated that multiple potential uses for ultrasound technology in DIEP flap reconstruction including preoperative perforator mapping, evaluation of the superficial inferior epigastric system and as a potential adjunct in flap delay procedures. Available studies suggest that ultrasound compares favorably to other widely-used imaging modalities for these indications.

Conclusion This article presents an in-depth review of the current applications of ultrasound in the preoperative planning of DIEP flaps and explores some potential areas for future investigation.



Publication History

Received: 31 May 2021

Accepted: 03 November 2021

Article published online:
28 January 2022

© 2022. Thieme. All rights reserved.

Thieme Medical Publishers, Inc.
333 Seventh Avenue, 18th Floor, New York, NY 10001, USA

 
  • References

  • 1 Knox ADC, Ho AL, Leung L. et al. Comparison of outcomes following autologous breast reconstruction using the DIEP and pedicled TRAM flaps: a 12-year clinical retrospective study and literature review. Plast Reconstr Surg 2016; 138 (01) 16-28
  • 2 Man L-X, Selber JC, Serletti JM. Abdominal wall following free TRAM or DIEP flap reconstruction: a meta-analysis and critical review. Plast Reconstr Surg 2009; 124 (03) 752-764
  • 3 Leyngold MM. Is unipedicled transverse rectus abdominis myocutaneous flap obsolete owing to superiority of DIEP flap?. Ann Plast Surg 2018; 80 (6S, Suppl 6): S418-S420
  • 4 Rozen WM, Palmer KP, Suami H. et al. The DIEA branching pattern and its relationship to perforators: the importance of preoperative computed tomographic angiography for DIEA perforator flaps. Plast Reconstr Surg 2008; 121 (02) 367-373
  • 5 Moon HK, Taylor GI. The vascular anatomy of rectus abdominis musculocutaneous flaps based on the deep superior epigastric system. Plast Reconstr Surg 1988; 82 (05) 815-832
  • 6 Phillips TJ, Stella DL, Rozen WM, Ashton M, Taylor GI. Abdominal wall CT angiography: a detailed account of a newly established preoperative imaging technique. Radiology 2008; 249 (01) 32-44
  • 7 Lam DL, Mitsumori LM, Neligan PC, Warren BH, Shuman WP, Dubinsky TJ. Pre-operative CT angiography and three-dimensional image post processing for deep inferior epigastric perforator flap breast reconstructive surgery. Br J Radiol 2012; 85 (1020): e1293-e1297
  • 8 Karunanithy N, Rose V, Lim AKP, Mitchell A. CT angiography of inferior epigastric and gluteal perforating arteries before free flap breast reconstruction. Radiographics 2011; 31 (05) 1307-1319
  • 9 Uppal RS, Casaer B, Van Landuyt K, Blondeel P. The efficacy of preoperative mapping of perforators in reducing operative times and complications in perforator flap breast reconstruction. J Plast Reconstr Aesthet Surg 2009; 62 (07) 859-864
  • 10 Teunis T, Heerma van Voss MR, Kon M, van Maurik JFMM. CT-angiography prior to DIEP flap breast reconstruction: a systematic review and meta-analysis. Microsurgery 2013; 33 (06) 496-502
  • 11 Malhotra A, Chhaya N, Nsiah-Sarbeng P, Mosahebi A. CT-guided deep inferior epigastric perforator (DIEP) flap localization – better for the patient, the surgeon, and the hospital. Clin Radiol 2013; 68 (02) 131-138
  • 12 Taylor GI, Doyle M, McCarten G. The Doppler probe for planning flaps: anatomical study and clinical applications. Br J Plast Surg 1990; 43 (01) 1-16
  • 13 Blondeel PN, Beyens G, Verhaeghe R. et al. Doppler flowmetry in the planning of perforator flaps. Br J Plast Surg 1998; 51 (03) 202-209
  • 14 Giunta RE, Geisweid A, Feller AM. The value of preoperative Doppler sonography for planning free perforator flaps. Plast Reconstr Surg 2000; 105 (07) 2381-2386
  • 15 Gunnarsson GL, Tei T, Thomsen JB. Color Doppler ultrasonography-targeted perforator mapping and angiosome-based flap reconstruction. Ann Plast Surg 2016; 77 (04) 464-468
  • 16 Mathes DW, Neligan PC. Preoperative imaging techniques for perforator selection in abdomen-based microsurgical breast reconstruction. Clin Plast Surg 2010; 37 (04) 581-591 , xi
  • 17 Cina A, Salgarello M, Barone-Adesi L, Rinaldi P, Bonomo L. Planning breast reconstruction with deep inferior epigastric artery perforating vessels: multidetector CT angiography versus color Doppler US. Radiology 2010; 255 (03) 979-987
  • 18 Pafitanis G, Pawa A, Mohanna P-N, Din AH. The Butterly iQ: An ultra-simplified color Doppler ultrasound for bedside pre-operative perforator mapping in DIEP flap breast reconstruction. J Plast Reconstr Aesthet Surg 2020; 73 (05) 983-1007
  • 19 Mijuskovic B, Tremp M, Heimer MM. et al. Color Doppler ultrasound and computed tomographic angiography for perforator mapping in DIEP flap breast reconstruction revisited: a cohort study. J Plast Reconstr Aesthet Surg 2019; 72 (10) 1632-1639
  • 20 Rozen WM, Phillips TJ, Ashton MW, Stella DL, Gibson RN, Taylor GI. Preoperative imaging for DIEA perforator flaps: a comparative study of computed tomographic angiography and doppler ultrasound. Plast Reconstr Surg 2008; 121 (1, Suppl): 1-8
  • 21 Kiely J, Kumar M, Wade RG. The accuracy of different modalities of perforator mapping for unilateral DIEP flap breast reconstruction: a systematic review and meta-analysis. J Plast Reconstr Aesthet Surg 2021; 74 (05) 945-956
  • 22 Feng S, Min P, Grassetti L. et al. A Prospective head-to-head comparison of color Doppler ultrasound and computed tomographic angiography in the preoperative planning of lower extremity perforator flaps. Plast Reconstr Surg 2016; 137 (01) 335-347
  • 23 Aubry S, Pauchot J, Kastler A, Laurent O, Tropet Y, Runge M. Preoperative imaging in the planning of deep inferior epigastric artery perforator flap surgery. Skeletal Radiol 2013; 42 (03) 319-327
  • 24 Kikuchi N, Murakami G, Kashiwa H, Homma K, Sato TJ, Ogino T. Morphometrical study of the arterial perforators of the deep inferior epigastric perforator flap. Surg Radiol Anat 2001; 23 (06) 375-381
  • 25 Pennington DG, Rome P, Kitchener P. Predicting results of DIEP flap reconstruction: the flap viability index. J Plast Reconstr Aesthet Surg 2012; 65 (11) 1490-1495
  • 26 Dusseldorp JR, Pennington DG. Quantifying blood flow in the DIEP flap: an ultrasonographic study. Plast Reconstr Surg Glob Open 2014; 2 (10) e228
  • 27 Visscher K, Boyd K, Ross DC, Amann J, Temple C. Refining perforator selection for DIEP breast reconstruction using transit time flow volume measurements. J Reconstr Microsurg 2010; 26 (05) 285-290
  • 28 Figus A, Ramakrishnan V, Rubino C. Hemodynamic changes in the microcirculation of DIEP flaps. Ann Plast Surg 2008; 60 (06) 644-648
  • 29 Gravvanis A, Tsoutsos D, Papanikolaou G, Diab A, Lambropoulou P, Karakitsos D. Refining perforator selection for deep inferior epigastric perforator flap: the impact of the dominant venous perforator. Microsurgery 2014; 34 (03) 169-176
  • 30 Rubino C, Ramakrishnan V, Figus A, Bulla A, Coscia V, Cavazzuti MA. Flap size/flow rate relationship in perforator flaps and its importance in DIEAP flap drainage. J Plast Reconstr Aesthet Surg 2009; 62 (12) 1666-1670
  • 31 Wade RG, Watford J, Wormald JCR, Bramhall RJ, Figus A. Perforator mapping reduces the operative time of DIEP flap breast reconstruction: a systematic review and meta-analysis of preoperative ultrasound, computed tomography and magnetic resonance angiography. J Plast Reconstr Aesthet Surg 2018; 71 (04) 468-477
  • 32 Blondeel PN. One hundred free DIEP flap breast reconstructions: a personal experience. Br J Plast Surg 1999; 52 (02) 104-111
  • 33 Hummelink S, Hoogeveen YL, Schultze Kool LJ, Ulrich DJO. A new and innovative method of preoperatively planning and projecting vascular anatomy in DIEP flap breast reconstruction: a randomized controlled trial. Plast Reconstr Surg 2019; 143 (06) 1151e-1158e
  • 34 Klasson S, Svensson H, Malm K, Wassélius J, Velander P. Preoperative CT angiography versus Doppler ultrasound mapping of abdominal perforator in DIEP breast reconstructions: a randomized prospective study. J Plast Reconstr Aesthet Surg 2015; 68 (06) 782-786
  • 35 Offodile II AC, Chatterjee A, Vallejo S, Fisher CS, Tchou JC, Guo L. A cost-utility analysis of the use of preoperative computed tomographic angiography in abdomen-based perforator flap breast reconstruction. Plast Reconstr Surg 2015; 135 (04) 662e-669e
  • 36 Gregorič M, Flis V, Milotić F, Mrđa B, Štirn B, Arnež ZM. Delaying the superficial inferior epigastric artery flap: a solution to the problem of the small calibre of the donor artery. J Plast Reconstr Aesthet Surg 2011; 64 (09) 1181-1186
  • 37 Casey III WJ, Chew RT, Rebecca AM, Smith AA, Collins JM, Pockaj BA. Advantages of preoperative computed tomography in deep inferior epigastric artery perforator flap breast reconstruction. Plast Reconstr Surg 2009; 123 (04) 1148-1155
  • 38 Wang D, Gao T, Liu L. et al. Thin superficial inferior epigastric artery perforator flap for reconstruction of the tongue. Br J Oral Maxillofac Surg 2020; 58 (08) 992-996
  • 39 Ayhan S, Oktar SO, Tuncer S, Yucel C, Kandal S, Demirtas Y. Correlation between vessel diameters of superficial and deep inferior epigastric systems: Doppler ultrasound assessment. J Plast Reconstr Aesthet Surg 2009; 62 (09) 1140-1147
  • 40 Figus A, Wade RG, Gorton L, Rubino C, Griffiths MG, Ramakrishnan VV. Venous perforators in DIEAP flaps: an observational anatomical study using duplex ultrasonography. J Plast Reconstr Aesthet Surg 2012; 65 (08) 1051-1059
  • 41 Zavlin D, Jubbal KT, Ellsworth IV WA, Spiegel AJ. Breast reconstruction with DIEP and SIEA flaps in patients with prior abdominal liposuction. Microsurgery 2018; 38 (04) 413-418
  • 42 Munhoz AM, Pellarin L, Montag E. et al. Superficial inferior epigastric artery (SIEA) free flap using perforator vessels as a recipient site: clinical implications in autologous breast reconstruction. Am J Surg 2011; 202 (05) 612-617
  • 43 Rozen WM, Chubb D, Grinsell D, Ashton MW. The variability of the Superficial Inferior Epigastric Artery (SIEA) and its angiosome: a clinical anatomical study. Microsurgery 2010; 30 (05) 386-391
  • 44 Rohde C, Keller A. Novel technique for venous augmentation in a free deep inferior epigastric perforator flap. Ann Plast Surg 2005; 55 (05) 528-530
  • 45 Sadik KW, Pasko J, Cohen A, Cacioppo J. Predictive value of SIEV caliber and superficial venous dominance in free DIEP flaps. J Reconstr Microsurg 2013; 29 (01) 57-61
  • 46 Pignatti M, Pinto V, Giorgini FA. et al. Meta-analysis of the effects of venous super-drainage in deep inferior epigastric artery perforator flaps for breast reconstruction. Microsurgery 2021; 41 (02) 186-195
  • 47 Fukaya E, Kuwatsuru R, Iimura H, Ihara K, Sakurai H. Imaging of the superficial inferior epigastric vascular anatomy and preoperative planning for the SIEA flap using MDCTA. J Plast Reconstr Aesthet Surg 2011; 64 (01) 63-68
  • 48 Restifo RJ, Ward BA, Scoutt LM, Brown JM, Taylor KJW. Clinical Studies. Timing, magnitude, and utility of surgical delay in the TRAM flap: II. Clinical studies. Plast Reconstr Surg 1997; 99 (05) 1217-1223
  • 49 Shakir S, Spencer AB, Kozak GM, Jablonka EM, Kanchwala SK. Make your own deep inferior epigastric artery perforator flap: perforator delay improves deep inferior epigastric artery perforator flap reliability. Plast Reconstr Surg Glob Open 2019; 7 (11) e2478
  • 50 Christiano JG, Rosson GD. Clinical experience with the delay phenomenon in autologous breast reconstruction with the deep inferior epigastric artery perforator flap. Microsurgery 2010; 30 (07) 526-531
  • 51 Rozen WM, Ashton MW, Stella DL, Phillips TJ, Taylor GI. The accuracy of computed tomographic angiography for mapping the perforators of the DIEA: a cadaveric study. Plast Reconstr Surg 2008; 122 (02) 363-369
  • 52 Rubino C, Coscia V, Cavazzuti AM, Canu V. Haemodynamic enhancement in perforator flaps: the inversion phenomenon and its clinical significance. A study of the relation of blood velocity and flow between pedicle and perforator vessels in perforator flaps. J Plast Reconstr Aesthet Surg 2006; 59 (06) 636-643