Download PDF
J Am Acad Audiol 2001; 12(01): 1-6
DOI: 10.1055/s-0041-1741114
Original Article

Effects of Monaural versus Binaural Stimulation on P300 Scalp Topography in Elderly Listeners

C. Renee Downs
Department of Communication Sciences and Disorders, East Carolina University, Greenville, North Carolina
,
Murvin R. Hymel
Department of Communication Sciences and Disorders, East Carolina University, Greenville, North Carolina
,
Jerry L. Cranford
Department of Communication Sciences and Disorders, East Carolina University, Greenville, North Carolina
› Author Affiliations
› Further Information
  PDF Download  Permissions and Reprints

Abstract

The P300 event-related potential was recorded from groups of young and elderly listeners in response to monaural and binaural stimulation. An oddball stimulus paradigm was used to record responses from 19 scalp locations. When listening to binaural stimuli, the young group showed midline and central P300 amplitude maxima, whereas the elderly group exhibited maximal responses in the midline and parietal regions. With monaural stimulation, the young group's responses were similar to those obtained with binaural stimulation. The elderly group, however, showed evidence of a greater contralateral hemisphere response to monaural stimulation during the early part of the P300 response. These findings support the possibility that the P300 neural generators may change with age with respect to temporal onset characteristics or their orientation and strength.

Abbreviations: EEG = electroencephalographic, GFP = global field power

Key Words

Auditory event-related potentials - auditory evoked potentials - brain map - elderly - P300 - scalp topography


Publication History

Article published online:
28 February 2022

© 2001. American Academy of Audiology. This article is published by Thieme.

Thieme Medical Publishers, Inc.
333 Seventh Avenue, 18th Floor, New York, NY 10001, USA

 

  • REFERENCES

  • Anderer P, Semlitsch HV, Saletu B. (1996). Multichannel auditory event-related brain potentials: effects of normal aging on the scalp distribution of N1, P2, N2 and P300 latencies and amplitudes. Electroencephalogr Clin Neurophysiol 99:458-472.
  • Ball S, Marsh J, Schubarth G, Brown W, Strandburg R. (1989). Longitudinal P300 latency changes in Alzheimer's disease. J Gerontol 44:195-200.
  • Brown WS, Marsh JT, LaRue A. (1982). Event-related potentials in psychiatry: differentiating depression and dementia in the elderly. Bull Los Angeles Neurol Soc 47:91-107.
  • Brown WS, Marsh JT, LaRue A. (1983). Exponential electrophysiological aging: P3 latency. Electroencephalogr Clin Neurophysiol 55:277-285.
  • Cranford JL, Hymel MR. (1998). Pros and cons of brain mapping as a tool for investigating central auditory pathologies. Semin Hear 19:345-355.
  • Donchin E. (1981). Surprise!... surprise? Psychophysiology 18:493-513.
  • Ford JM, Pfefferbaum A. (1991). Event-related potentials and eyeblink responses in automatic and controlled processing: effects of age. Electroencephalogr Clin Neurophysiol 78:361-377.
  • Friedman D, Simpson G, Hamberger M. (1993). Age-related changes in scalp topography to novel and target stimuli. Psychophysiology 30:383-396.
  • Friedman D, Kazmerski V, Fabiani M. (1997). An overview of age-related changes in the scalp distribution of P3b. Electroencephalogr Clin Neurophysiol 104:498-513.
  • Goodin DS, Squires KC, Starr A. (1978). Long-latency event-related components of the auditory evoked potential in dementia. Brain 101:635-648.
  • Halgren E, Squires NK, Wilson CL, Rohrbaugh JW, Babb TL, Crandell PH. (1980). Endogenous potentials generated in the human hippocampal formation and amygdala by infrequent events. Science 210:803-805.
  • Holt LE, Raine A, Pa G, Schneider LS, Henderson VW, Pollock VE. (1995). P300 topography in Alzheimer's disease. Psychophysiology 32:257—265.
  • Hymel MR, Cranford JL, Stuart A. (1998). Effects of contralateral speech competition on auditory event-related potentials recorded from elderly listeners: brain map study. J Am Acad Audiol 9:385-397.
  • Iragui VJ, Kutas M, Mitchiner MR, Hillyard SA. (1993). Effects of aging on event-related brain potentials and reaction times in an auditory oddball task. Psychophysiology 30:10-22.
  • Jirsa RE, Clontz KB. (1990). Long latency auditory event-related potentials from children with auditory processing disorders. Ear Hear 11:222-292.
  • Knight RT. (1984). Decreased response to novel stimuli after prefrontal lesions in man. Electroencephalogr Clin Neurophysiol 59:9-20.
  • Kugler CFA, Taghavy A, Platt D. (1993). The event-related P300 potential analysis of cognitive human brain aging: a review. Gerontology 39:280-303.
  • Marvel JB, Jerger JF, Lew HL. (1992). Asymmetries in topographic brain maps of auditory evoked potentials in the elderly. J Am Acad Audiol 3:361-368.
  • Neshige R, Barrett G, Shibasaki H. (1988). Auditory long latency event-related potentials in Alzheimer's disease and multi-infarct dementia. J Neurol Neurosurg Psychiatry 51:1120-1125.
  • Pfefferbaum A, Ford JM, Wenegrat BG, Roth WT, Kopell BS. (1984). Clinical application of the P3 component of event-related potentials: I. Normal aging. Electroencephalogr Clin Neurophysiol 59:85-103.
  • Picton TW, Stuss DT, Champagne SC, Nelson RF. (1984). The effects of age on human event-related potentials. Psychophysiology 21:312-325.
  • Polich J. (1997). EEG and ERP assessment of normal aging. Electroencephalogr Clin Neurophysiol 104:244-256.
  • Polich J, Ladish C, Bloom FE. (1990). P300 assessment of early Alzheimer's disease. Electroencephalogr Clin Neurophysiol 77:179-189.
  • Polich J, Alexander JE, Bauer LO, Kuperman S. Morzorati S, O'Connor SJ, Porjesz B, Rohrbaugh J, Begleiter H. (1997). P300 topography of amplitude/latency correlations. Brain Topogr 9:275-282.
  • Sangal RB, Sangal JM. (1996). Topography of auditory and visual P300 in normal adults. Clin Electroencephalogr 27:145-150.
  • Semlitsch HV, Anderer R, Schuster P, Presslich O. (1986). A solution for reliable and valid reduction of ocular artifacts applied to the P300 ERP. Psychophysiology 23:695-703.
  • Skrandies W. (1989). Data reduction of multichannel fields: global field power and principle component analysis. Brain Topogr 2:73-80.
  • Skrandies W (1990). Global field power and topographic similarity. Brain Topogr 3:137-141.
  • Smith DBD, Michalewski HJ, Brent GA, Thompson LW. (1980). Auditory averaged evoked potentials and aging: factors of stimulus, task and topography. Biol Psychol 11:135-151.
  • Smith ME, Halgren E, Sokolik M, Baudena P, Musolino A, Liegeois-Chauvel C, Chauvel P. (1990). The intracranial topography of the P3 event-related potential during auditory oddball. Electroencephalogr Clin Neurophysiol 76:235-248.
  • Squires KC, Hecox KE. (1983). Electrophysiological evaluation of higher level auditory processing. Semin Hear 4:415-433.
  • Squires KC, Wickens C, Squires NK, Donchin E. (1976). The effects of stimulus sequence on the waveform of the cortical event-related potential. Science 193:1142-1145.
  • Sutton S, Braren M, Zubin J, John ER. (1965). Evoked-potential correlates of stimulus uncertainty. Science 150:1187-1188.
  • Syndulko K, Hansen EC, Cohen SC, Pearce JW, Goldberg Z, Montan B, Tourtellotte WW, Potoin AR. (1982). Long-latency event-related potentials in normal aging and dementia. In: Courjan J, Mauguiere F, Revol M, eds. Clinical Applications of Evoked Potentials in Neurology. New York: Raven Press, 279-285.
  • Vesco KK, Bone RC, Ryan JC, Polich J. (1993). P300 in young and elderly subjects: auditory frequency and intensity effects. Electroencephalogr Clin Neurophysiol 88:302-308.
  • Yingling CD, Hosobuchi Y. (1984). A subcortical correlate of P300 in man. Electroencephalogr Clin Neurophysiol 59:72-76.