Int J Angiol
DOI: 10.1055/s-0042-1758193
Case Report

May–Thurner Syndrome: A Forgotten Cause of Deep Vein Thrombosis

Iwan Junianto
1   Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia
2   Department of Cardiology and Vascular Medicine, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia
,
1   Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia
2   Department of Cardiology and Vascular Medicine, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia
3   Department of Cardiology and Vascular Medicine, Teluk Bintuni Hospital, Papua Barat, Indonesia
,
Hananto Andriantoro
1   Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia
2   Department of Cardiology and Vascular Medicine, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia
,
1   Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia
2   Department of Cardiology and Vascular Medicine, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia
,
1   Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia
2   Department of Cardiology and Vascular Medicine, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia
,
Suko Adiarto
1   Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia
2   Department of Cardiology and Vascular Medicine, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia
› Author Affiliations

Abstract

May–Thurner syndrome (MTS) is a relatively rare vascular condition that is characterized by external compression of the left common iliac vein by the right common iliac artery against the fifth lumbar vertebra. This condition slows the blood flow and is a predisposing factor for deep vein thrombosis (DVT). The key to its successful treatment is to remove the clot and fix the anatomical lesion. If this MTS diagnosis is missed, the recurrence of thrombosis will lead to significant morbidity and mortality. We report a case of 70-year-old female who had left leg DVT caused by MTS and was treated with catheter-directed thrombolysis along with long-term anticoagulation.



Publication History

Article published online:
02 November 2022

© 2022. International College of Angiology. This article is published by Thieme.

Thieme Medical Publishers, Inc.
333 Seventh Avenue, 18th Floor, New York, NY 10001, USA

 
  • References

  • 1 Mazzolai L, Aboyans V, Ageno W. et al. Diagnosis and management of acute deep vein thrombosis: a joint consensus document from the European Society of Cardiology working groups of aorta and peripheral vascular diseases and pulmonary circulation and right ventricular function. Eur Heart J 2018; 39 (47) 4208-4218
  • 2 Baburao A, Singh A, Babu A, Pandey A. May-Thurner syndrome: a forgotten cause of venous thromboembolism. Indian J Crit Care Med 2020; 24 (01) 66-68
  • 3 Brazeau NF, Harvey HB, Pinto EG, Deipolyi A, Hesketh RL, Oklu R. May-Thurner syndrome: diagnosis and management. Vasa 2013; 42 (02) 96-105
  • 4 Liddell RP, Evans NS. May-Thurner syndrome. Vasc Med 2018; 23 (05) 493-496
  • 5 Kibbe MR, Ujiki M, Goodwin AL, Eskandari M, Yao J, Matsumura J. Iliac vein compression in an asymptomatic patient population. J Vasc Surg 2004; 39 (05) 937-943
  • 6 O'Sullivan GJ, Semba CP, Bittner CA. et al. Endovascular management of iliac vein compression (May-Thurner) syndrome. J Vasc Interv Radiol 2000; 11 (07) 823-836
  • 7 Thijs W, Rabe KF, Rosendaal FR, Middeldorp S. Predominance of left-sided deep vein thrombosis and body weight. J Thromb Haemost 2010; 8 (09) 2083-2084
  • 8 Kalu S, Shah P, Natarajan A, Nwankwo N, Mustafa U, Hussain N. May-Thurner syndrome: a case report and review of the literature. Case Reports in Vascular Medicine 2013; pp.1–5. doi: 10.1155/2013/740182. = 15
  • 9 Uhl JF, Gillot C, Chahim M. Anatomical variations of the femoral vein. J Vasc Surg 2010; 52 (03) 714-719
  • 10 Fleck D, Albadawi H, Shamoun F, Knuttinen G, Naidu S, Oklu R. Catheter-directed thrombolysis of deep vein thrombosis: literature review and practice considerations. Cardiovasc Diagn Ther 2017; 7 (3, Suppl 3): S228-S237
  • 11 Patterson BO, Hinchliffe R, Loftus IM, Thompson MM, Holt PJE. Indications for catheter-directed thrombolysis in the management of acute proximal deep venous thrombosis. Arterioscler Thromb Vasc Biol 2010; 30 (04) 669-674
  • 12 Berger A, Jaffe JW, York TN. Iliac compression syndrome treated with stent placement. J Vasc Surg 1995; 21 (03) 510-514
  • 13 Mewissen MW, Seabrook GR, Meissner MH, Cynamon J, Labropoulos N, Haughton SH. Catheter-directed thrombolysis for lower extremity deep venous thrombosis: report of a national multicenter registry. Radiology 1999; 211 (01) 39-49
  • 14 Vedantham S, Millward SF, Cardella JF. et al; Society of Interventional Radiology. Society of Interventional Radiology position statement: treatment of acute iliofemoral deep vein thrombosis with use of adjunctive catheter-directed intrathrombus thrombolysis. J Vasc Interv Radiol 2006; 17 (04) 613-616
  • 15 Meissner MH, Gloviczki P, Comerota AJ. et al. Early thrombus removal strategies for acute deep venous thrombosis: clinical practice guidelines of the Society for Vascular Surgery and the American Venous Forum. J Vasc Surg 2012; 55 (01) 449-462
  • 16 Knuttinen MG, Naidu S, Oklu R. et al. May-Thurner: diagnosis and endovascular management. Cardiovasc Diagn Ther 2017; 7 (3, Suppl 3): S159-S164
  • 17 Neglén P, Hollis KC, Olivier J, Raju S. Stenting of the venous outflow in chronic venous disease: long-term stent-related outcome, clinical, and hemodynamic result. J Vasc Surg 2007; 46 (05) 979-990
  • 18 Hager ES, Yuo T, Tahara R. et al. Outcomes of endovascular intervention for May-Thurner syndrome. J Vasc Surg Venous Lymphat Disord 2013; 1 (03) 270-275