Synthesis 1990; 1990(4): 299-301
DOI: 10.1055/s-1990-26857
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A Convenient One-Pot Conversion of N-Protected Amino Acids and Peptides into Alcohols

George Kokotos*
  • *Department of Chemistry, University of Athens, 13A Navarinou Str., Athens 10680, Greece
Further Information

Publication History

Publication Date:
17 September 2002 (online)

N-Protected amino acids and peptides are converted to alcohols by chemoselective reduction of their corresponding mixed anhydrides with sodium borohydride in tetrahydrofuran with dropwise addition of methanol.

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