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Synthesis 1990; 1990(8): 663-666
DOI: 10.1055/s-1990-26974
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A Novel Synthesis of Acyclic N-(α-Hydroxybenzyl)benzamides

Alan R. Katritzky* , M. Suresh Chander Rao
  • *Department of Chemistry, University of Florida, Gainesville, FL 32611, USA
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Publication History

Publication Date:
17 September 2002 (online)

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N-Hydroxybenzamides 1 react with hydroxymethylbenzotriazole (2) to give (benzotriazol-1-yl)methyl derivatives 3. These are converted by aryl Grignard reagents into acyclic N-(α-hydroxybenzyl)-benzamides 6.

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