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Synlett 1994; 1994(9): 745-747
DOI: 10.1055/s-1994-22995
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Synthesis of Acyclic, Multifunctionalized α,α′-Disecondary Ethers with Full Control of Chemo-, Regio- and Enantioselectivity

Arndt Brandes* , Ulrike Eggert, H. M. R. Hoffmann
  • *Department of Organic Chemistry, University of Hannover, Schneiderberg 1 B D-30167 Hannover, Germany
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Publication Date:
18 September 2002 (online)

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Acyclic, multifunctionalized α,α′-disecondary ethers are synthesized with full control of chemo-, regio- and enantioselectivity. The synthesis starts from easily accessible epoxy tosylates and highly functionalized secondary alcohols. The reaction is simple and can be scaled up.

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