Download PDF
Synlett 1996; 1996(1): 55-56
DOI: 10.1055/s-1996-5319
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

A One-pot Aromatic Vicarious Nucleophilic Substitution of Hydrogen/Alkylation Route to Substituted Nitrobenzenes

Nicholas J. Lawrence* , John Liddle, David A. Jackson
  • *Dept. of Chemistry, UMIST, PO Box 88, Manchester, M60 1QD, UK; Email: Nick.Lawrence@umist.ac.uk
Further Information

Publication History

Publication Date:
31 December 2000 (online)

  PDF Download  Permissions and Reprints All articles of this category

A series of novel one-pot vicarious nucleophilic substitution/alkylation reactions are described. Reaction of the enolate of ethyl 2-chloropropionate with nitrobenzene followed by subsequent reaction with an alkylating agents gives a series of esters bearing a quaternary centre.

vicarious nucleophilic substitution - alkylation - α-arylpropionic acids

      >