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Synlett 1996; 1996(8): 793-795
DOI: 10.1055/s-1996-5523
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Direct Protection of 1,2-Diols from α-Diketones

Nina L. Douglas, Steven V. Ley* , Helen M. I. Osborn, Dafydd R. Owen, Henning W. M. Priepke, Stuart L. Warriner
  • *Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK
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Publication History

Publication Date:
31 December 2000 (online)

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α-Diketones react directly with 1,2-diols to 1,2-give diacetal structures under acid catalysed reaction conditions. These 1,2-diacetals serve as a highly effective protecting group for vicinal diols.

α-Diketone - 1,2-diacetals - vicinal diol protection

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