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Synlett 1996; 1996(10): 1017-1018
DOI: 10.1055/s-1996-5639
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Highly Enantioselective Synthesis of NH-3-Amino-4-Substituted Azetidin-2-ones via a Two-Step Staudinger Reaction

Elisa Bandini, Giorgio Martelli1 , Giuseppe Spunta, Mauro Panunzio2
  • 1.Co.C.E.A.-C.N.R. Via Gobetti 101 - 40129 Bologna, Italy
  • 2Università and C.S.F.M.-C.N.R. Dip. Ciamician Via Selmi, 2 - 40126 Bologna, Italy, Fax +39(51)259456, e-mail panunzio@ciamserv.ciam.unibo.it
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Publication History

Publication Date:
31 December 2000 (online)

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New conditions for the Staudinger reaction provide N-unsubstituted 3-amino-4-substituted-β-lactams in satisfactory yields with complete trans-selectivity and high facial diastereoselectivity.

Staudinger - chiral - azetidinones - synthesis

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