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Synthesis 1999; 1999(2): 330-335
DOI: 10.1055/s-1999-3392
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Bis-Tetrahydrofurans from Carbohydrates via Iodoetherification and Iodine Substitution

Philippe Bertrand* , Hanadi El Sukkari, Jean-Pierre Gesson, Brigitte Renoux
  • *Laboratoire de Chimie 12, Université de Poitiers et CNRS, 40 avenue du Recteur Pineau, F-86022 Poitiers Cedex, France; Fax +33(5)49 45 35 01; E-mail: jean-pierre.gesson@cri.univ-poitiers.fr
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Publication Date:
31 December 1999 (online)

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Iodocyclization followed by nucleophilic displacement of iodine affords mainly trans-2,5-substituted THF related to annonaceous acetogenins.

carbohydrates - bis-tetrahydrofurans - iodoetherification - nucleophilic displacement of iodine - trans-2,5-disubstituted tetrahydrofurans

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