J Reconstr Microsurg 2001; 17(1): 017-026
DOI: 10.1055/s-2001-12684
Copyright © 2001 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Free Vascularized Fibular Graft vs. Ilizarov Method for Post-Traumatic Tibial Bone Defect

Kazuhiko Yokoyama, Moritoshi Itoman, Koushin Nakamura, Tatsuro Tsukamoto, Yasuyuki Saita, Shinichi Aoki
  • Department of Orthopedic Surgery, School of Medicine, Kitasato University, Kanagawa, Japan
Further Information

Publication History

Publication Date:
31 December 2001 (online)

ABSTRACT

From 1991 to 1996, four free vascularized fibular grafts (FVFG) and four callus distraction (CD) techniques were performed for post-traumatic tibial defects at the authors' institute. They attempted to discern any differences of results between FVFGs and CDs for post-traumatic tibial defects. The mean defect length of the FVFG and CD groups were 7.3 cm and 4.6 cm, respectively (p < 0.05). They selected as contributing factors: external fixation time, complication rate, hospital charge, union rate, and functional score (Puno's criteria), in order to compare the treatment of FVFG with that of CD. The external fixation times of the FVFG and CD groups were 176 days and 261 days, respectively. One septic non-union after refracture of the grafted fibula occurred in the FVFG group. Two non-unions (50 percent) at the docking site occurred in the CD group. The mean total costs of the FVFG and CD groups were ¥=7,398,536 (US $68,505) and ¥=11,798,153 (US $109,242), respectively. The union rates of both groups were 75 percent and 100 percent, respectively. The mean functional scores of both groups were 69.5 and 88.8 points, respectively. The functional results of the FVFG group were as follows: one patient showed good results; one, fair; and two, poor. The functional results of the CD group were as follows: two patients showed excellent results; one, good; and one, fair. Both the costs and the functional outcomes between the two groups did not significantly differ.

No clear differences between the two treatment groups could be determined. However, many more cases are needed to establish statistically significant differences between both methods.

REFERENCES

  • 1 Schmitz J P, Hollinger J O. The critical size defect as an experimental model for craniomandibulofascial nonunions.  Clin Orthop . 1985;  205 299
  • 2 Christian E P, Bosse M J, Robb G. Reconstruction of large diaphyseal defects, without free fibular transfer, in grade-IIIB tibial fractures.  J Bone Joint Surg . 1989;  71A 994
  • 3 Reckling F W, Waters III H C. Treatment of non-unions of fractures of the tibial diaphysis by posterolateral cortical cancellous bone-grafting.  J Bone Joint Surg . 1980;  62A 936
  • 4 Weinberg H, Roth V G, Robin G C, Floman Y. Early fibular bypass procedures (tibiofibular synostosis) for massive bone loss in war injuries.  J Trauma . 1979;  19 177
  • 5 Agiza A-RH. Treatment of tibial osteomyelitic defects and infected pseudarthroses by the Huntington fibular transference operation.  J Bone Joint Surg . 1981;  63A 814
  • 6 Chmell M J, McAndrew M P, Thomas R, Schwarz H S. Structural allografts for reconstruction of lower extremity open fractures with 10 centimeters or more of acute segmental defects.  J Orthop Trauma . 1995;  9 222
  • 7 Chapman M W. Closed intramedullary bone-grafting and nailing of segmental defects of the femur: a report of three cases.  J Bone Joint Surg . 1980;  62A 1004
  • 8 Taylor G I, Miller G DH, Ham F J. The free vascularized bone graft: a clinical extension of microvascular techniques.  Plast Reconstr Surg . 1975;  55 533
  • 9 Weiland A J. Current concepts review: vascularized free bone transplants.  J Bone Joint Surg . 1981;  63A 166
  • 10 Weiland A J, Moore R, Daniel R K. Vascularized bone autografts: experience with 41 cases.  Clin Orthop . 1983;  174 87
  • 11 Chung Y K, Chung S. Ipsilateral island fibula transfer for segmental tibial defects: antegrade and retrograde fashion.  Plast Reconstr Surg . 1998;  101 375
  • 12 Paley D, Catagni M A, Argnani F. Ilizarov treatment of tibial nonunions with bone loss.  Clin Orthop . 1989;  241 146
  • 13 Neggar L, Chevalley F, Blanc C H, Livio J-J. Treatment of large bone defects with the Ilizarov technique.  J Trauma . 1993;  34 390
  • 14 Johnson E E, Urist M R, Finerman G AM. Repair of segmental defects of the tibia with cancellous bone grafts augmented with human bone morphogenetic protein: a preliminary report.  Clin Orthop . 1988;  236 249
  • 15 Yasko A W, Lane J M, Fellinger E J. The healing of segmental bone defects, induced by recombinant human bone morphogenetic protein (rhBMP-2): a radiographic, histological, and biomechanical study in rats.  J Bone Joint Surg . 1992;  74A 659
  • 16 Dahlin C, Linde A, Gottlow J, Nyman S. Healing of bone defects by guided tissue regeneration.  Plast Reconstr Surg . 1988;  81 672
  • 17 Gugala Z, Gogolewski S. Regeneration of segmental diaphyseal defects in sheep tibiae using resorbable polymetric membranes: a preliminary study.  J Orthop Trauma . 1999;  13 187
  • 18 Hofmann G O, Kirschner M H, Bühren V, Land W. Allogenic vascularized transplantation of a human femoral diaphysis under cyclosporin A immunosuppression.  Transpl Int . 1995;  8 418
  • 19 Gustilo R B, Mendoza R, Williams D N. Problems in the management of type III (severe) open fractures: a new classification of type III open fractures.  J Trauma . 1984;  24 742
  • 20 Betz A M, Stock W, Hierner R, Baumgart R. Primary shortening with secondary limb lengthening in severe injuries of the lower leg: a six year experience.  Microsurgery . 1993;  14 446
  • 21 Giebel G. Resektiondebridement am Unterschenkel mit kompensatorischer Kallusdistraktion.  Unfallchirurg . 1991;  94 401
  • 22 Klemm K W. Antibiotic beads chains.  Clin Orthop . 1993;  95 63-76
  • 23 Boda A. Antibiotic irrigation-perfusion treatment for chronic osteomyelitis.  Arch Orthop Traumat Surg . 1979;  95 31
  • 24 Puno R M, Grossfeld S L, Henry S L. Functional outcome of patients with salvageable limbs with grades III-B and III-C open fractures of the tibia.  Microsurgery . 1996;  17 167
  • 25 Paley D. Problems, obstacles, and complications of limb lengthening by Ilizarov technique.  Clin Orthop . 1990;  250 81
  • 26 Watson J T, Anders M, Moed B R. Management strategies for bone loss in tibial shaft fractures.  Clin Orthop . 1995;  315 138
  • 27 Toh C-L, Jupiter J B. The infected nonunion of the tibia.  Clin Orthop . 1995;  315 176
  • 28 McKee M D, Yoo D, Schemitsch E H. Health status after Ilizarov reconstruction of post-traumatic lower-limb deformity.  J Bone Joint Surg . 1998;  80B 360
  • 29 Yaremchuk M J, Brumback R J, Manson P N. Acute and definitive management of traumatic osteocutaneous defects of the lower extremity.  Plast Reconstr Surg . 1987;  80 100
  • 30 Khouri R K, Shaw W W. Monitoring of free flaps with surface-temperature recordings: is it reliable?.  Plast Reconstr Surg . 1992;  89 495
  • 31 Benacquista T, Kasabian A K, Karp N S. The fate of lower extremities with failed free flaps.  Plast Reconstr Surg . 1996;  98 834
  • 32 Minami A, Kimura T, Matsumoto O, Kutsumi K. Fracture through united vascularized bone grafts.  J Reconstr Microsurg . 1993;  9 227
  • 33 Saleh M, Rees A. Bifocal surgery for deformity and bone loss after lower-limb fractures: comparison of bone-transport and compression-distraction methods.  J Bone Joint Surg . 1995;  77B 429
  • 34 Dendrinos G K, Kontos S, Lyritsis E. Use of the Ilizarov technique for treatment of non-union of the tibia associated with infection.  J Bone Joint Surg . 1995;  77A 835
  • 35 Lenoble E, Lewertowski J M, Goutallier D. Reconstruction of compound tibial and soft tissue loss using a traction histogenesis technique.  J Trauma . 1995;  39 356
  • 36 Toh S, Tubo K, Nakajima K. Reconstruction of the traumatic bone defect or pseudarthrosis of the tibia using vascularized fibula graft (in Japanese).  J Jpn Orthop Assoc . 1998;  72 S163
  • 37 Jupiter J B, Palumbo M A, Nunley J A. Secondary reconstruction after vascularized fibular transfer.  J Bone Joint Surg . 1993;  75A 1442
  • 38 Low C-K, Pho R WH, Kour A-K. Infection of vascularized fibular grafts.  Clin Orthop . 1996;  323 163
  • 39 Minehara H, Yokoyama K, Sekiguchi M. Bone transport combined with free flap reconstruction and antibiotic bead spacers for type IIIB open tibial fractures: case report.  J Trauma . 1998;  44 1103
  • 40 Hedeström S-Å, Lidgren L, Törholm C, Önmerrfält R. Antibiotic containing bone cement beads in the treatment of deep muscle and skeletal infections.  Acta Orthop Scand . 1980;  51 863
  • 41 Minami A, Kaneda K, Itoga H. Treatment of infected segmental defect of long bone with vascularized bone transfer.  J Reconstr Microsurg . 1992;  8 75
  • 42 Jupiter J B, Kour A K, Palumbo M D, Yaremchuk M J. Limb reconstruction by free-tissue transfer combined with the Ilizarov method.  J Bone Joint Surg . 1991;  88 943
  • 43 Lowenberg D W, Feibel R J, Louie K W, Eshima I. Combined muscle flap and Ilizarov reconstruction for bone and soft tissue defects.  Clin Orthop . 1996;  332 37
  • 44 Raschke M, Mann J W, Oedekoven G, Claudi B. Segmental transport after unreamed intramedullary nailing: preliminary report of a ``monorail'' system.  Clin Orthop . 1992;  282 233
  • 45 Baumgart R, Betz A, Schweiberer L. A fully implantable motorized intramedullary nail for limb lengthening and bone transport.  Clin Orthop . 1997;  343 135
    >