Lithium Perchlorate Catalyzed Regioselective Ring Opening of Aziridines with Sodium Azide and Sodium Cyanide

Abstract

Aziridines react smoothly with sodium azide and sodium cyanide in the presence of catalytic amount of lithium perchlorate under essentially mild and neutral reaction conditions to afford the corresponding β-azido and β-cyanoamines in high yields with high regioselectivity.

Keywords

lithium perchlorate - aziridines - regioselective - β-azidoamines

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