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Synthesis 2004(17): 2784-2786  
DOI: 10.1055/s-2004-834880
SHORTPAPER
© Georg Thieme Verlag Stuttgart · New York

Facile and Chemoselective Microwave-Assisted Cleavage of Oximes to Their Corresponding Carbonyl Compounds Using N,N′ -Dibromo- N,N′-1,3-propylene- bis[(4-methylphenyl)sulfonamide] as a Deoximating Reagent

Ardeshir Khazaei*, Abbas Amini Manesh, Amir H oshang Ghasemi
Department of Chemistry, Faculty of Sciences, Bu-Ali Sina University, P. O. Box 65178-4119, Hamadan, Iran
e-Mail: khazaei_1326@yahoo.com;
Further Information

Publication History

Received 11 June 2004
Publication Date:
15 October 2004 (online)

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Abstract

Aldoximes and ketoximes are converted to the parent carbonyl compounds in good yields when treated with N,N′-dibromo-N,N′-1,3-propylene-bis[(4-methylphenyl)sulfonamide] (2) under microwave irradiation. The simple workup minimizes the loss of product and oximes have been selectively oxidized in the presence of alcohols and alkenes.

Key words

aldoximes - carbonyl compounds - ketoximes - microwave irradiation - selective

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