Flüssigkeitsmanagement - Pathophysiologische Grundlagen sowie intra- und perioperatives Monitoring

Zusammenfassung

Die pathophysiologischen Effekte der Flüssigkeits-und Volumentherapie beruhen auf den pharmakologischen Eigenschaften und der Menge der perioperativ infundierten Flüssigkeiten. Durch Veränderung der Gefäßpermeabiltät im Stressstoffwechsel führen Fehldosierungen, als auch Produktnebenwirkungen, zu einer Einschränkung der Organfunktion mit konsekutiv beeinträchtigtem postoperativen Outcome des Patienten. Durch ein situativ angepasstes Monitoring kann hier Kenntnis über den Volumenstatus des Patienten gewonnen werden, um Therapiefehler zu vermeiden.

Abstract

The pathophsiological effects of fluid and volume therapy depend on the pharmacological properties and the amount of the fluid infused during an operation. Because of changes of vessel permeability in stress metabolism, not only inappropriate doses but also substance side effects can lead to impaired organ function with a subsequent detrimental outcome for the patient. By means of a monitoring system adapted to the individual situation, knowledge about the patient's volume status can be obtained and therapeutic errors avoided.

Schlüsselwörter

Flüssigkeitsmanagement - Monitoring-Verfahren; Hyper- und Hypovolämie; Thermodilution; Volumenstatus; Volumentherapie - Pathophysiologie

Keywords:

Fluid management - monitoring - hyper- and hypovolemia - thermodilution - volume status - volume therapy - pathophysiology

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