Enantioselective Synthesis of Oxazolidinones

R. P. Reddy; H. M. L. Davies

doi:10.1055/s-2006-955744

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Synfacts 2007(1): 0020-0020
DOI: 10.1055/s-2006-955744

Synthesis of Heterocycles

Enantioselective Synthesis of Oxazolidinones

Contributor(s): Victor Snieckus, Heiko Scharl
R. P. Reddy, H. M. L. Davies*
State University of New York at Buffalo, USA

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Publication History

Publication Date:
15 December 2006 (online)

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Significance

An efficient and enantioselective oxazolidinone synthesis via an intramolecular Rh₂(S-TCPTAD)₄-catalyzed C-H amination is reported. The enantioselectivity is modest and the scope of the method was not fully evaluated.