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Planta Med 1985; 51(2): 157-158
DOI: 10.1055/s-2007-969434
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© Georg Thieme Verlag Stuttgart · New York

Isolation and Hypoglycemic Activity of Lithospermans A, B and C, Glycans of Lithospermum erythrorhizon Roots1

Chohachi Konno, Takakazu Mizuno, Hiroshi Hikino
  • Pharmaceutical Institute, Tohoku University, Aoba-yama, Sendai, Japan
1 Antidiabetes drugs, Part 3. Also Part 79 in the validity of the Oriental medicines
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Publication History

1984

1984

Publication Date:
26 February 2007 (online)

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Abstract

A water extract of the Oriental crude drug “shikon”, Lithospermum erythrorhizon roots, remarkably diminished the plasma sugar level in mice. Fractionation of the extract by monitoring the activity yielded three glycans, lithospermans A, B and C. These glycans exerted marked hypoglycemic effects in normal and alloxan-induced hyperglycemic mice.

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