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Planta Med 1985; 51(3): 212-214
DOI: 10.1055/s-2007-969459
Research Articles

© Georg Thieme Verlag Stuttgart · New York

Alkaloids of Lolium temulentum: Isolation, Identification and Pharmacological Activity1

G. Dannhardt, L. Steindl
  • Universität Regensburg, Naturwissenschaftliche Fakultät IV, Postfach 397, D-8400 Regensburg
1 Part of lectures given at: 2nd Internat. Conference of Chemistry and Biotechnology of Biologically Active Natural Products, Budapest, Aug. 15-19, 1983 and Jahrestagung der DPhG, Düsseldorf, Sept. 26-29, 1984
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Publication History

1984

1985

Publication Date:
26 February 2007 (online)

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Abstract

Analysis of the overground part of Lolium temulentum L. led to the isolation of two main alkaloids: loline (B) and perloline (D). Loline and two minor alkaloids (A, C) are strictly localized in the caryopses, whereas perloline is found mainly in the stems. In tests for CNS activity loline · 2 HCl was uneffective in displacing prazosin, serotonine, QNB, bungarotoxin and flunitrazepam from binding sites of calf brain.

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