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Planta Med 1985; 51(3): 253-255
DOI: 10.1055/s-2007-969471
DOI: 10.1055/s-2007-969471
Research Articles
© Georg Thieme Verlag Stuttgart · New York
Muscle Relaxant Properties of Aqueous Extract of Lippia multiflora
Further Information
Publication History
1984
1984
Publication Date:
26 February 2007 (online)
Abstract
Aqueous leaf extracts of Lippia multiflora administered intraperitoneally produced a profound calming effect, muscle relaxing action, and significant reduction in the spontaneous locomotor activity of mice measured in the Ugo Basile activity cage. The extract (0.25-1.0 g kg-1) reduced amphetamine induced locomotor activity in mice. The extract (0.5-1.0 mg ml-1) inhibited contractions of the isolated rat diaphragm in response to the phrenic nerve stimulation. The muscle relaxant effect was considered to be primarily responsible for the calming effect, bordering on tranquilizing activity observed in mice and rats.